89922-38-3Relevant academic research and scientific papers
Diastereoselective production of homoallylic alcohols bearing quaternary centers from γ-substituted allylic indiums and ketones
Babu, Srinivasarao Arulananda,Yasuda, Makoto,Baba, Akio
, p. 10264 - 10267 (2008/03/28)
(Chemical Equation Presented) Highly stereoselective In-employed addition of γ-substituted allylic halides (cyclohexenyl halides, cinnamyl halides, and ethyl 4-bromocrotonate) to ketones is established to produce homoallyl alcohols bearing quaternary cent
Catalytic enantioselective intermolecular reductive aldol reaction to ketones
Zhao, Dongbo,Oisaki, Kounosuke,Kanai, Motomu,Shibasaki, Masakatsu
, p. 1403 - 1407 (2007/10/03)
We describe the first example of a catalytic enantioselective intermolecular reductive aldol reaction. Three types of reactions were studied: (1) reactions between acetophenone and methyl acrylate; (2) reactions between symmetric ketones and β-substituted
Dramatic ligand effect in catalytic asymmetric reductive aldol reaction of allenic esters to ketones
Zhao, Dongbo,Oisaki, Kounosuke,Kanai, Motomu,Shibasaki, Masakatsu
, p. 14440 - 14441 (2008/02/02)
A general catalytic asymmetric reductive aldol reaction of allenic esters to ketones is described. Two distinct constitutional isomers were selectively produced depending on the reaction conditions. A combination of CuOAc/(R)-DTBM-SEGPHOS/PCy3
Regioselectivity in the Reformatsky Reaction of 4-Bromocrotonate. Role of the Catalyst and the Solvent in the Normal vs. Abnormal Modes of Addition to Carbonyl Substrates
Rice, Leonard E.,Boston, M.Craig,Finklea, Harry O.,Suder, Billy Jo,Frazier, James O.,Hudlicky, Tomas
, p. 1845 - 1848 (2007/10/02)
The regioselectivity of addition of the organozinc reagent derived from ethyl 4-bromocrotonate to 10 carbonyl substrates was found to be dependent on the polarity of solvents and the hardness of metal catalysts.
