899694-59-8

Basic information

• Product Name: 2-(2-bromophenyl)-5-methyl-1H-indole
• Synonyms: 2-(2-bromophenyl)-5-methyl-1H-indole
• CAS NO: 899694-59-8
• Molecular Weight: 286.171
• Mol File: 899694-59-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(2-bromophenyl)-5-methyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromophenyl)-5-methyl-1H-indole(899694-59-8)
• EPA Substance Registry System: 2-(2-bromophenyl)-5-methyl-1H-indole(899694-59-8)

Safety Data

• Hazardous Substances Data: 899694-59-8(Hazardous Substances Data)

Upstream product

• 2142-69-0 2-bromophenyl methyl ketone 
• 539-44-6 N-4-methylphenylhydrazine 
• 637-60-5 p-tolylhydrazine hydrochloride 
• 106-49-0 p-toluidine 

Downstream Products

• 1224635-42-0 8-methyl-6-phenyl-11H-benzo[a]carbazole 
• 1415639-66-5 8-chloro-6-phenyl-11H-benzo[a]carbazole 
• 1385821-16-8 10-methyl-6-phenylindolo[1,2-c]quinazoline 
• 1469538-20-2 6-(4-chlorophenyl)-10-methylindolo[1,2-c]quinazoline 
• 1600518-89-5 C₁₆H₁₄BrN 
• 1430809-00-9 10-methyl-6-(3-nitrophenyl)indolo[1,2-c]quinazoline 
• 1430808-99-3 6-(4-fluorophenyl)-10-methylindolo[1,2-c]quinazoline 
• 1385821-17-9 10-methyl-6-p-tolylindolo[1,2-c]quinazoline 
• 1430808-97-1 10-methyl-6-propylindolo[1,2-c]quinazoline 

Relevant articles and documents

Oxygenophilic Lewis Acid Promoted Synthesis of 2-Arylindoles from Anilines and Cyanoepoxides in Alcohol

A convenient synthetic method to indoles from anilines and cyanoepoxides was developed under the catalysis of BF3·OEt2 or AlCl3 in alcohols. The reaction involves a tandem reaction of the regiospecific ring-opening of cyanoepoxides with anilines, elimination of cyanide, intramolecular aromatic electrophilic substitution, and water elimination. The Lewis acid generated protic acid is an efficient catalyst. The method features readily accessible starting materials, wide substrate scope, transition-metal-free environment, and regiospecificity in the ring-opening of cyanoepoxides.

Preparation method of indole compounds

The invention provides a preparation method of indole compounds. 2-cyanoethylene oxide compounds and arylamine react under the catalysis effect of lewis acid (boron trifluoride diethyl etherate or aluminum trichloride) to obtain corresponding indole compo