89971-88-0

Upstream product

• 1256-06-0 (2S,5R,6R)-benzyl-3,3-dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 100-39-0 benzyl bromide 
• 132-98-9 penicillin V potassium 

Downstream Products

• 121534-49-4 benzyl 2-<(2R,3R)-2-acetonylsulphonyl-4-oxo-3-phenoxyacetamidoazetidin-1-yl>-2-metylbut-2-enoate 
• 121534-50-7 benzyl 2-<(2R,3S)-2-acetonylsulphonyl-4-oxo-3-phenoxyacetamidoazetidin-1-yl>glyoxylate 
• 121534-48-3 benzyl 2-<(3S,4R)-2-oxo-3-phenoxyacetamido-4-sulphinoacetamido-4-sulphinoazetidin-1-yl>-2-methylbut-2-enoate 
• 39650-26-5 phenoxymethylpenicillinic acid 1,1-dioxide 

Relevant academic research and scientific papers

STUDIES RELATED TO PENICILLINS. PART 27. A STRATEGY FOR THE CONVERSION OF 1,1-DIOXIDES OF PENICILLANATES INTO 1,1-DIOXIDES OF 3-METHYLCEPH-3-EM-4-CARBOXYLATES

Methodology for the conversion of benzyl (3S,5R)-penicillinate 1,1-dioxide (2b) into (6R)-4-benzyloxycarbonyl-3-methylceph-3-em 1,1-dioxide (3b) has been devised.In the process, the 3,4-double bond of the product was constructed by a reductive carbonyl-ca

OXIDATION STUDIES ON BETA-LACTAM ANTIBIOTICS SYNTHESIS OF PHENAM AND CEPHEM SULFOXIDES AND SULFONES

Penicillin and cephalosporin sulfoxides are conveniently prepared by oxidation of the respective penicillin or cephalosporin in methylene chloride using hydrogen peroxide and acetic acid.Replacement of the acetic acid by formic acid produces the respectiv