89988-46-5Relevant academic research and scientific papers
Comparative studies for selective deprotection of the N-arylideneamino moiety from heterocyclic amides: Kinetic and theoretical studies
George, Bobby J.,Dib, Hicham H.,Abdallah, Mariam R.,Ibrahim, Maher R.,Khalil, Nasser S.,Ibrahim, Yehia A.,Al-Awadi, Nouria A.
, p. 1182 - 1192 (2007/10/03)
The kinetics, product analysis and theoretical studies for selective deprotection of N-arylideneamino pyridone, pyrimidinone and triazinone systems were carried out. Their reactivities were compared with each other and with related compounds previously studied. This reaction represents an efficient, clean and general synthetic procedure for the protection and selective synthesis of potential biologically active pyridines, pyrimidines and triazines and their derivatives.
Synthesis and Structure of as-Triazinoquinazolines, II.
Badawy, Mohamed A.,Abdel-Hady, Sayed A. L.,Eid, Mohga M.,Ibrahim, Yehia A.
, p. 1083 - 1088 (2007/10/02)
4-Amino-3-(methylthio)-6-R-1,2,4-triazin-5(4H)-ones 6-10 react with anthranilic acid to yield the 1-amino-3-R-2H-as-triazinoquinazoline-2,6(1H)-diones 17-21 rather than the expected as-triazinobenzotriazepines 12-16.Compounds 17-21 were deaminated into compounds 22-26.Heating of the N-benzylidene derivatives of 6-10 (27-31) with anthranilic acid also led to the formation of 22-26 with extrusion of benzonitrile.
Synthesis and Structure of as-Triazinoquinazolines, I.
Abdel-Hady, Sayed A. L.,Badawy, Mohamed A.,Ibrahim, Yehia A.,Pfleiderer, Wolfgang
, p. 1077 - 1082 (2007/10/02)
3-(Methylthio)-6-R-1,2,4-triazin-5(2H)-ones 1-6 have been converted into the 3-R-2H-as-triazinoquinazoline-2,6(1H)-diones 8-13 upon cyclocondensation with anthranilic acid.Reaction of 2-methyl-3-(methylthio)-6-phenyl-1,2,4-triazin-5(2H)-one (23) wi
