90012-40-1

Basic information

• Product Name: 2-PHENYL-5-P-TOLYL-2H-PYRAZOL-3-YLAMINE
• Synonyms: 5-AMINO-3-(4-METHYLPHENYL)-1-PHENYLPYRAZOLE;2-PHENYL-5-P-TOLYL-2H-PYRAZOL-3-YLAMINE;1-PHENYL-3-P-TOLYL-1H-PYRAZOL-5-AMINE;BUTTPARK 88\11-96;SALOR-INT L317942-1EA;3-(4-Methylphenyl)-1-phenyl-1H-pyrazol-5-amine;5-Amino-3-(4-methylphenyl)-1-phenylpyrazole 97%;5-(4-methylphenyl)-2-phenylpyrazol-3-amine
• CAS NO: 90012-40-1
• Molecular Formula: C₁₆H₁₅N₃
• Molecular Weight: 249.31
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrazoles;Building Blocks;C12 to C37;Chemical Synthesis;Heterocyclic Building Blocks
• Mol File: 90012-40-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 173-176 °C(lit.)
• Boiling Point: 460.4 °C at 760 mmHg
• Flash Point: 232.3 °C
• Appearance: /
• Density: 1.15 g/cm³
• Vapor Pressure: 1.16E-08mmHg at 25°C
• Refractive Index: 1.635
• CAS DataBase Reference: 2-PHENYL-5-P-TOLYL-2H-PYRAZOL-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-5-P-TOLYL-2H-PYRAZOL-3-YLAMINE(90012-40-1)
• EPA Substance Registry System: 2-PHENYL-5-P-TOLYL-2H-PYRAZOL-3-YLAMINE(90012-40-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 90012-40-1(Hazardous Substances Data)

Usage

Uses

5-Amino-3-(4-methylphenyl)-1-phenylpyrazole may be used in the preparation of N′-[4-formyl-3-(4-methylphenyl)-1-phenyl-1H-pyrazol-5-yl]-N,N-dimethylimidoformamide, an intermediate for preparing 5-amino-3-(4-methylphenyl)-1-phenyl-1H-pyrazole-4-carbaldehyde.

General Description

5-Amino-3-(4-methylphenyl)-1-phenylpyrazole (3-(4-methylphenyl)-1-phenyl-1H-pyrazol-5-amine) belongs to a family of 5-aminopyrazole derivatives, which are bioactive agents. They find a wide range of applications in the pharmaceutical and agrochemical industries. It can be prepared by refluxing a mixture of p-methyl-benzoylacetonitrile and phenylhydrazine in ethanol.

InChI:InChI=1/C16H15N3/c1-12-7-9-13(10-8-12)15-11-16(17)19(18-15)14-5-3-2-4-6-14/h2-11H,17H2,1H3

Upstream product

• 100-63-0 phenylhydrazine 
• 17196-75-7 3-amino-3-p-tolylacrylonitrile 
• 7391-28-8 p-tolueneacetonitrile 

Downstream Products

• 851052-50-1 1-(1,3-diphenylpyrazol-5-yl)thiourea 
• 1400634-69-6 3-(4-methylphenyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1602492-67-0 (E)-1,2-bis(4-iodo-1-phenyl-3-p-tolyl-1H-pyrazol-5-yl)diazene 
• 1602492-77-2 (E)-1,2-bis(1-phenyl-3-p-tolyl-1H-pyrazol-5-yl)diazene 

Relevant articles and documents

A clean and rapid synthesis of 5-amino and 5-alkoxycarbonylpyrazoles using montomorillonite under acid free conditions

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