900159-00-4Relevant articles and documents
The neuroprotective activity of GPE tripeptide analogues does not correlate with glutamate receptor binding affinity
Alonso De Diego, Sergio A.,Gutierrez-Rodriguez, Marta,Perez de Vega, M. Jesus,Gonzalez-Muniz, Rosario,Herranz, Rosario,Martin-Martinez, Mercedes,Cenarruzabeitia, Edurne,Frechilla, Diana,Rio, Joaquin Del,Jimeno, M. Luisa,Garcia-Lopez, M. Teresa
, p. 3396 - 3400 (2007/10/03)
The influence of several modifications on the GPE tripeptide structure upon the binding to GluRs and on their neuroprotective effects has been studied. The results indicated that the prevention of neuronal death showed by GPE and some analogues is not dir