90035-41-9Relevant academic research and scientific papers
The Synthesis of Peptide β-Lactams as Potential Protease Inhibitors
Wharton, Clifford J.,Wrigglesworth, Roger,Rowe, Michael
, p. 29 - 39 (2007/10/02)
β-Lactam analogues of a peptide which is a substrate/inhibitor of Angiotensin Converting Enzyme (ACE) have been designed as potential inhibitors of the enzyme.The synthesis of a series of these compounds is described and their absolute stereochemistry has been assigned by a combination of X-ray crystallography, chemical shift correlations, and nuclear Overhauser effect (n.O.e.) studies.
