90047-52-2

Basic information

• Product Name: 1,2-Benzenedimethanol, 3-methoxy-
• CAS NO: 90047-52-2
• Molecular Formula: C9H12O3
• Molecular Weight: 168.192
• Mol File: 90047-52-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedimethanol, 3-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedimethanol, 3-methoxy-(90047-52-2)
• EPA Substance Registry System: 1,2-Benzenedimethanol, 3-methoxy-(90047-52-2)

Safety Data

• Hazardous Substances Data: 90047-52-2(Hazardous Substances Data)

Usage

General Description

1,2-Benzenedimethanol, 3-methoxy-, also known as vanillin, is a naturally occurring compound found in the vanilla bean. It is widely used as a flavoring agent in foods, beverages, and pharmaceuticals. Vanillin has a sweet, vanilla-like aroma and taste, and is commonly used to enhance the flavor of various products. It is also used in the production of fragrances and cosmetics. Vanillin has been studied for its potential antioxidant, anti-inflammatory, and antimicrobial properties, making it a compound of interest in the fields of medicine and health. Additionally, it is used in the synthesis of various chemicals and pharmaceuticals.

Upstream product

• 14963-97-4 3-methoxyphthalic acid 
• 71887-28-0 methyl 2-(bromomethyl)-3-methoxybenzoate 
• 42981-93-1 3-methoxy-2-methylbenzoic acid methyl ester 
• 55289-06-0 3-methoxy-2-methylbenzoic acid 
• 99-06-9 3-Carboxyphenol 
• 50-00-0 formaldehyd 
• 586-38-9 3-Methoxybenzoic acid 
• 28281-58-5 7-methoxyisobenzofuran-1(3H)-one 
• 71785-96-1 2,3-bisbromomethylanisole 
• 2944-49-2 2,3-dimethylanisole 
• 4792-33-0 4-methoxyphthalide 
• 130662-47-4 2,3-bis(acetoxymethyl)anisole 
• 526-75-0 2,3-Dimethylphenol 
• 14963-96-3 3-methoxyphthalic anhydride 

Downstream Products

• 4792-33-0 4-methoxyphthalide 
• 28281-58-5 7-methoxyisobenzofuran-1(3H)-one 
• 180461-61-4 3-methoxy phthalaldehyde 
• 90047-45-3 3-methoxy-1,2-bis-(cyanomethyl)benzene 
• 189166-81-2 Benzoic acid (1S,2S,9R,10R,13S)-9,10-diacetoxy-13-((2R,3S)-3-benzoylamino-3-phenyl-2-triethylsilanyloxy-propionyloxy)-1-hydroxy-4-methoxy-12,15,15-trimethyl-tricyclo[9.3.1.0^3,8]pentadeca-3⁽⁸⁾,4,6,11-tetraen-2-yl ester 
• 189166-82-3 Benzoic acid (1R,2R,9S,10S,13R)-9,10-diacetoxy-13-((2R,3S)-3-benzoylamino-3-phenyl-2-triethylsilanyloxy-propionyloxy)-1-hydroxy-4-methoxy-12,15,15-trimethyl-tricyclo[9.3.1.0^3,8]pentadeca-3⁽⁸⁾,4,6,11-tetraen-2-yl ester 
• 189166-72-1 [5-(tert-Butyl-dimethyl-silanyloxymethyl)-4,6,6-trimethyl-cyclohexa-1,4-dienyl]-[2-(tert-butyl-diphenyl-silanyloxymethyl)-6-methoxy-phenyl]-methanol 
• 189166-71-0 2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-methoxy-benzaldehyde 
• 932745-87-4 diethyl 2-(benzyloxycarbonylamino)-4-methoxyindane-2-phosphonate 

Relevant articles and documents

Assessment of the regioselectivity in the condensation reaction of unsymmetrical o-phthaldialdehydes with alanine

One approach for the synthesis of isoindolinones, a privileged bioactive heterocyclic core structure, involves a condensation reaction of o-phthaldialdehydes with a suitable nitrogen-containing nucleophile. This fascinating reaction is revisited here in the context of the use of o-phthaldialdehydes that contain additional substituents in the aromatic ring leading to a detailed analysis of the regioselectivity of the reaction. Eleven monosubstituted o-phthaldialdehydes were synthesised and reacted with alanine. The regioselectivity observed across the eleven substrates led to the design of a disubstituted substrate that reacted with very high control. A gram-scale reaction followed by esterification gave one major regioisomer in high yield. In addition, the regioselectivity observed on reaction of two novel monodeuterated substrates led to an increased mechanistic understanding.

Inhibitors of phenylalanine ammonia-lyase: Substituted derivatives of 2-aminoindane-2-phosphonic acid and 1-aminobenzylphosphonic acid

Six derivatives of 2-aminoindane-2-phosphonic acid and 1-aminobenzylphosphonic acid were synthesized. The compounds were tested both as inhibitors of buckwheat phenylalanine ammonia-lyase (in vitro) and as inhibitors of anthocyanin biosynthesis (in vivo). (±)-2-Amino-4-bromoindane-2-phosphonic acid was found to be the strongest inhibitor from investigated compounds. The results obtained are a basis for design of phenylalanine ammonia-lyase inhibitors useful in the enzyme structure studies in photo labelling experiments.

WATER-SOLUBLE TRIAZOLE FUNGICIDE

A triazole compound of the general formula (I) or a pharmacologically acceptable salt thereof: [wherein,X represents a group of formula X-OH which has antifungal activity,L represents a -(adjacently substituted C6-C10 aryl)-CH2-group and the like, andR represents a -P(=O) (OH)2 group and the like.