90087-77-7

Usage

Uses

Used in Pharmaceutical Industry:
3-Pyrrolidin-1-ylacrylic acid methyl ester is used as an intermediate in the synthesis of pharmaceuticals for its potential applications in medicinal chemistry.
Used in Agrochemical Industry:
3-Pyrrolidin-1-ylacrylic acid methyl ester is used as an intermediate in the synthesis of agrochemicals for its potential applications in the development of pesticides and other agricultural products.
Used in Organic Synthesis:
3-Pyrrolidin-1-ylacrylic acid methyl ester is used as a building block in organic synthesis for its potential applications in the creation of new compounds and materials.

InChI:InChI=1/C8H13NO2/c1-11-8(10)4-7-9-5-2-3-6-9/h4,7H,2-3,5-6H2,1H3/b7-4+

Upstream product

• 123-75-1 pyrrolidine 
• 1441063-42-8 (E)-methyl 3-(2-oxopyridin-1 (2H)-yl)acrylate 
• 340257-71-8 (5-formyl-benzo[1,3]dioxol-2-yl)-acetic acid methyl ester 
• 340257-73-0 (4-formyl-benzo[1,3]dioxol-2-yl)-acetic acid methyl ester 
• 340257-67-2 methyl 2-(1,3-benzodioxol-2-yl)acetate 

Downstream Products

• 132371-02-9 dimethyl 3-benzenesulphonyl-2-pyrrolidinomethylidinylglutarate 
• 2055-52-9 methyl 1-phenyl-1H-1,2,3-triazole-4-carboxylate 
• 118459-15-7 5-(4-chlorophenyl)-3-pyrrolidino-1,2,4-triazine 
• 118459-14-6 4-carbomethoxy-6-(4-chlorophenyl)-2-(methylsulfonyl)pyridine 
• 90920-52-8 1-(4-nitro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid methyl ester 
• 227959-99-1 methyl 1-(4-methylphenyl)-1H-1,2,3-triazole-4-carboxylate 
• 87565-77-3 methyl 2-methyl-4-pyrrolidino-6-hydroxybenzoate 
• 244238-99-1 2-(4-methoxy-phenyl)-1,2-dihydro-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester 
• 244239-06-3 2-methyl-6-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid dimethyl ester 
• 244239-05-2 2-(2-nitro-phenyl)-pyridine-3,5-dicarboxylic acid 5-ethyl ester 3-methyl ester 
• 4967-77-5 methyl 1,2,3-triazole-4-carboxylate 
• 78504-05-9 (furan-2-yl)(pyrrolidin-1-yl)methanone 
• 69340-21-2 (pyrrolidin-1-yl)(thiophen-2-yl)methanone 
• 136758-26-4 4-(3-Nitro-phenyl)-5-oxo-2-pyrrolidin-1-yl-4,5-dihydro-indeno[1,2-b]pyran-3-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Nucleophile-catalyzed additions to activated triple bonds. protection of lactams, imides, and nucleosides with MocVinyl and related groups

Additions of lactams, imides, (S)-4-benzyl-1,3-oxazolidin-2-one, 2-pyridone, pyrimidine-2,4-diones (AZT derivatives), or inosines to the electron-deficient triple bonds of methyl propynoate, tert-butyl propynoate, 3-butyn-2-one, N-propynoylmorpholine, or

Bocdene and mocdene derivatives of catechols and catecholamines.

[reaction in text] Catechols react chemoselectively, in the presence of either alcohols, 1,2-diols, or simple phenols, with tert-butyl propynoate and with methyl propynoate to give 2-Boc-ethylidene (Bocdene) and 2-Moc-ethylidene (Mocdene) acetals, respectively, in 96-100% yields within 30 min at room temperature, provided that 150 mol % of DMAP is added. Cleavage of these acetals with pyrrolidine readily takes place (at room temperature!) in 95-100% yields. By taking advantage of the features of Bocdene acetals, novel catecholamine-related phosphate mimetics have been prepared.