90121-92-9Relevant academic research and scientific papers
Syn-β-hydroxyallylic silanes from terminal epoxide α-lithiation-silylation and alkenylation: Application to the tetrahydrofuran portion of the lytophilippines
Hodgson, David M.,Salik, Saifullah
supporting information, p. 4402 - 4405 (2012/11/06)
Lithiation-in situ silylation of terminal epoxides using lithium 2,2,6,6-tetramethylpiperidide in combination with phenyldimethyl(or diethyl)silyl chloride provides a direct process for the synthesis of trans-α,β-epoxysilanes, which undergo α-ring opening with alkenylcoppers to give syn-β-hydroxyallylic silanes. The chemistry is applied in an annulation approach to the C10-C19 tetrahydrofuran-containing portion of the lytophilippines.
Stereospecific Rearrangement of 2,2-Disubstituted Vinylsilane Epoxides to the Silyl Enol Ethers of 2,2-Disubstituted Aldehydes
Fleming, Ian,Newton, Trevor W.
, p. 119 - 124 (2007/10/02)
The Z- and E-2-ethyl-2-methylvinylsilane epoxides (5a) and (5b) rearrange stereospecifically in the presence of boron trifluoride-diethyl ether to the Z- and E-silyl enol ethers, (6a) and (6b), respectively, of 2-methylbutanal.These silyl enol ethers reac
