901408-74-0

Upstream product

• 98-54-4 para-tert-butylphenol 
• 70-11-1 α-bromoacetophenone 
• 3282-32-4 2-diazo-acetophenone 
• 109-99-9 tetrahydrofuran 

Downstream Products

• 1202634-06-7 5-(tert-butyl)-3-phenylbenzofuran 
• 1613483-75-2 2-(4-(tert-butyl)phenoxy)-1-phenyl-2-(3-(trifluoromethyl)phenyl)ethanone 
• 1613483-76-3 4-(1-(4-(tert-butyl)phenoxy)-2-oxo-2-phenylethyl)benzonitrile 
• 1613483-74-1 ethyl 4-(1-(4-(tert-butyl)phenoxy)-2-oxo-2-phenylethyl)benzoate 
• 1613483-73-0 2-(4-(tert-butyl)phenoxy)-2-(3,4-dimethoxyphenyl)-1-phenylethanone 
• 1613483-72-9 2-(4-(tert-butyl)phenoxy)-2-(4-methoxyphenyl)-1-phenylethanone 
• 1613483-94-5 5-(tert-butyl)-3-phenyl-2-(3-(trifluoromethyl)phenyl)benzofuran 
• 1613483-93-4 5-(tert-butyl)-2-(3,4-dimethoxyphenyl)-3-phenylbenzofuran 
• 1613483-92-3 5-(tert-butyl)-2-(4-methoxyphenyl)-3-phenylbenzofuran 

Relevant academic research and scientific papers

Synthesis of benzofurans from the cyclodehydration of α-phenoxy ketones mediated by Eaton’s reagent

Cyclodehydration of α-phenoxy ketones promoted by Eaton’s reagent (phosphorus pentoxide–methanesulfonic acid) is used to prepare 3-substituted or 2,3-disubstituted benzofurans with moderate to excellent yields under mild conditions. The method provides a facile access to benzofurans from readily available starting materials such as phenols and α-bromo ketones. The reaction is highly efficient, which is attributed to the good reactivity and fluidity of Eaton’s reagent. The reaction can be applied to prepare naphthofurans, furanocoumarins, benzothiophenes, and benzopyrans.

Palladium-catalyzed α-arylation of aryloxyketones for the synthesis of 2,3-Disubstituted benzofurans

A highly efficient palladium-catalyzed α-arylation of aryloxyketones has been developed, allowing for facile installation of various (hetero)aryl groups at C2 position in good to excellent yields. Subsequent cyclodehydration of the resulting α-arylated ar

Polycondensation of bis(diazocarbonyl) compounds with aromatic diols and cyclic ethers: Synthesis of new type of polyetherketones

A series of new polyetherketones was prepared by Rh-catalyzed polycondensation of bis(diazocarbonyl) compounds 1a-c with aromatic diols 2A-C in cyclic ethers (THF, THP, and 1,4-dioxane). In addition to the expected insertion of diazo-bearing carbon of 1a-

Novel one-pot synthesis of 3-Phenylnaphtho[2,3-b]furan and 3-phenylbenzofurans under microwave irradiation and solvent-free conditions

A one-pot synthesis of functionalized benzofurans has been developed via O-alkylation, carbon-carbon coupling/cyclization, and dehydration/olefination tandem reactions from phenacyl bromide and phenols under microwave irradiation and solvent-free conditio