90211-85-1Relevant articles and documents
Stereoselective Synthesis of Squalamine Dessulfate
Moriarty, Robert M.,Enache, Livia A.,Kinney, William A.,Allen, Craig S.,Canary, James W.,et al.
, p. 5139 - 5142 (1995)
Squalamine dessulfate (24R) and the unnatural product squalamine dessulfate (24S) have been synthesized from stigmasterol.The key step is establishing the C24 stereochemistry is attachment of the sidechain at C22 using either (2R)- or (2S)-1,2-epoxy-3-met