90211-85-1

Upstream product

• 55123-01-8 (S)-(+)-1,2-epoxy-3-methylbutane 
• 85639-62-9 3α,5-cyclo-22-phenylsulfonyl-5α-23,24-bisnorcholan-6β-ol 6-methyl ether 
• 873-55-2 sodium benzenesulfonate 
• 51231-25-5 3α,5-cyclo-22-iodo-5α-23,24-bisnorcholan-6β-ol 6-methyl ether 
• 25819-77-6 (20S)-6β-methoxy-3α,5-cyclo-5α-pregnane-20-carbaldehyde 
• 51231-23-3 3α,5-cyclo-22-hydroxy-5α-23,24-bisnorcholan-6β-ol 6-methyl ether 
• 90211-82-8 (2S)-1-tosyloxy-3-methylbutan-2-ol 
• 17407-55-5 (S)-2-Hydroxy-3-methylbutanoic acid 
• 72-18-4 L-valine 
• 24347-56-6 (S)-3-methylbutane-1,2-diol 

Downstream Products

• 27460-26-0 24(R)-Hydroxycholesterol 

Relevant academic research and scientific papers

Stereoselective Synthesis of Squalamine Dessulfate

Squalamine dessulfate (24R) and the unnatural product squalamine dessulfate (24S) have been synthesized from stigmasterol.The key step is establishing the C24 stereochemistry is attachment of the sidechain at C22 using either (2R)- or (2S)-1,2-epoxy-3-met

A Stereoselective Synthesis and a Convenient Synthesis of Optically Pure (24 R)- and (24 S)-24-hydroxycholesterols

A new stereoselective synthesis of optically pure (24 S)-24-hydroxycholesterol (cerebrosterol) and (24 R)-24-hydroxycholesterol, using D- and L-valines as chiral sources, as well as a convenient synthesis, are described.