Stereoselective Synthesis of Squalamine Dessulfate

DOI: 10.1016/00404-0399(50)10116-

Source and publish data:

Tetrahedron Letters p. 5139 - 5142 (1995)

Update date:2022-08-02

Topics:

Authors:

Moriarty, Robert M.

Enache, Livia A.

Kinney, William A.

Allen, Craig S.

Canary, James W.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/00404-0399(50)10116-

Squalamine dessulfate (24R) and the unnatural product squalamine dessulfate (24S) have been synthesized from stigmasterol.The key step is establishing the C24 stereochemistry is attachment of the sidechain at C22 using either (2R)- or (2S)-1,2-epoxy-3-met

Full text of DOI:10.1016/00404-0399(50)10116-

Products guided by the article

Product name:(24R)-6β-methoxy-22-phenylsulfonyl-24-hydroxy-3α,5α-cyclocholestane

Cas No:90211-85-1

R&D Labs maybe for 90211-85-1

Shanghai PotentPharm Science and Technology Co.,Ltd

Contact:86-021-51969655

Address:Unit B, Building 18, No.300, Chuantu Rd,Pudong District, Shanghai 201202, China
Nantong Baokai Chemical Co., Ltd (Hangzhou Baokai Bio-Chemicals Co.,Ltd.)

Contact:+86-513-83886111

Address:No. 68 Suzhou road ,Binjiang Fine Chemical Industrial Park , Beixin town, Qidong city ,Jiangsu province
China Synchem Technology Co.,Ltd

website:http://www.cnsynchem.com

Contact:+86-0552-4929311

Address:No.217 Daqing Road
Anhui Biochem United Pharmaceutical Co., Ltd.

Contact:0086 551 5167062 / 5228268

Address:No. 30 Hongfeng Road, Hi-Tech Development Zone, Hefei (230088), China
SHAANXI FUJIE PHARMACEUTICAL CO.,LTD

website:http://www.fujiepharm.com

Contact:+86-29-63650906

Address:Yuanqu Yi Road, Qinghe Food Industrial Park, Sanyuan County, Shaanxi Province, China

Relevant to this article

Deacylation of Pyrrole and other Aromatic Ketones

Doi:10.1021/jo00189a002
(1984)
Diferrocenyl(hydroxy)oxazepines and diferrocenyl-4-aza-1,3-dienes in the reactions of 2,3-diferrocenyl-1-methylthiocyclopropenylium iodide with aromatic and aliphatic bis-1,4-N,O-nucleophiles

Doi:10.1016/j.poly.2019.07.019
(2019)
Synthesis and Evaluation of a New Series of 8-(2-Nitroaryl)Xanthines as Adenosine Receptor Ligands

Doi:10.1002/ddr.21317
(2016)
6-Cyano Analogues of Bedaquiline as Less Lipophilic and Potentially Safer Diarylquinolines for Tuberculosis

Doi:10.1021/acsmedchemlett.7b00196
(2017)
Stereoselective synthesis of oligo-α-(2,8)-sialic acids

Doi:10.1021/ja0613613
(2006)
Ruthenium-catalyzed asymmetric hydrogenation of N-Boc-indoles

Doi:10.1021/ol061039x
(2006)

Article Doi