903572-19-0Relevant academic research and scientific papers
A highly efficient protocol for the synthesis of N-aryl nucleobases using zinc oxide in ionic liquids
Zare,Hasaninejad,Khalafi-Nezhad,Moosavi-Zare,Beyzavi,Khedri,Asadi,Hayati,Asifi
experimental part, p. 461 - 469 (2010/08/20)
A highly efficient and simple method for the synthesis of N-aryl derivatives of pyrimidine and purine nucleobases via N-arylation of nucleobases using zinc oxide in 1-butyl-3-methylimidazolium bromide ([bmim]Br) under microwave as well as thermal conditio
New approach for the synthesis of 1-aryl- and 1-heteroaryl-5-nitrouracil derivatives
Gondela, Andrzej,Walczak, Krzysztof
, p. 2859 - 2864 (2007/10/03)
1-(2,4-Dinitrophenyl)-5-nitrouracil and its 3-methyl derivatives were synthesized and used as substrates in reaction with aromatic amines and amino pyridines. In the reaction of aniline with 1-(2,4-dinitrophenyl)-5-nitrouracil, only the acyclic adduct was isolated. When 1-(2,4-dinitrophenyl)-3-methyl-5-nitrouracil was treated with aniline and other aromatic amines or amino pyridines, the desired 1-aryl-5-nitrouracil derivatives were obtained in satisfactory yield. The influence of the free H-3 proton present in the uracil ring on the course of the reaction is discussed.
A convenient method for N-1 arylation of uracil derivatives
Gondela, Andrzej,Walczak, Krzysztof
, p. 4653 - 4657 (2007/10/03)
1-(4-Nitrophenyl)- and 1-(2,4-dinitrophenyl)uracil derivatives have been obtained by direct arylation of uracil and its 5-substituted derivatives using 1-fluoro-4-nitrobenzene or 1-fluoro-2,4-dinitrobenzene in the presence of a base. The application of the newly obtained uracil derivatives in further synthesis is also presented.
Microwave-assisted N-nitroarylation of some pyrimidine and purine nucleobases
Khalafi-Nezhad, Ali,Zare, Abdolkarim,Parhami, Abolfath,Rad Soltani, Mohammad Navid,Nejabat, Gholam Reza
, p. 979 - 985 (2007/10/03)
An efficient procedure for the synthesis of some N-nitroaryl derivatives of nucleobases via microwave-assisted N-nitroarylation of nucleobases in the presence of SiO2 and Cs2CO3 in DMSO, as the homogenizing solvent, is des
Regioselective N-arylation of some pyrimidine and purine nucleobases
Khalafi-Nezhad, Ali,Zare, Abdolkarim,Parhami, Abolfath,Soltani Rad, Mohammad Navid,Nejabat, Gholam Reza
, p. 3549 - 3562 (2007/10/03)
N-Arylation of some pyrimidine and purine nucleobases in the presence of SiO2 and Cs2CO3 under solvent-free as well as in solution conditions is described. In these conditions, N1-aryl pyrimidines and N9-aryl purines have
