90369-75-8

Usage

Uses

Used in Pharmaceutical Industry:
(3-Chloro-2-Methylphenyl)Methanol is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to contribute to the development of new drugs and improve the efficacy of existing medications.
Used in Agrochemical Industry:
(3-Chloro-2-Methylphenyl)Methanol is used as a building block in the production of agrochemicals, such as pesticides and herbicides, to help increase crop yields and protect plants from harmful organisms.
Used in Chemical Reactions:
(3-Chloro-2-Methylphenyl)Methanol is used as a reagent in chemical reactions, particularly in the synthesis of organic solvents and other industrial chemicals, due to its reactive nature and ability to form a variety of chemical bonds.
Used in Disinfectants and Antiseptic Products:
Leveraging its antimicrobial properties, (3-Chloro-2-Methylphenyl)Methanol is used in the formulation of disinfectants and antiseptic products to help prevent the spread of infections and maintain hygiene in various settings, such as healthcare facilities and households.

Upstream product

• 50-00-0 formaldehyd 
• 118-69-4 2,6-dichlorotoluene 
• 874-27-1 3-Chloro-2-methylbenzaldehyde 
• 54454-12-5 (3-chloro-2-methylphenyl)carbonitrile 
• 99586-84-2 methyl 2-methyl-3-chlorobenzoate 
• 7499-08-3 3-chloro-2-methylbenzoic acid 

Downstream Products

• 55676-89-6 2-methyl-3-chlorobenzyl chloride 
• 874-27-1 3-Chloro-2-methylbenzaldehyde 
• 90369-81-6 3,3'-bis(bromomethyl)-2,2'-dimethylbenzophenone 
• 90369-88-3 Bis(3-(mercaptomethyl)-2-methylphenyl) Ketone 
• 90369-93-0 C₁₉H₂₄N₄OS₂⁽²⁺⁾*2Br^(1-) 
• 90369-79-2 Bis(3-(methoxymethyl)-2-methylphenyl)methanol 
• 90369-82-7 Bis(3-(methoxymethyl)-2-methylphenyl)methane 
• 90369-80-5 Bis(3-(methoxymethyl)-2-methylphenyl) Ketone 
• 90369-83-8 Bis(3-(bromomethyl)-2-methylphenyl)methane 
• 90369-78-1 3-(Methoxymethyl)-2-methylbenzonitrile 
• 28746-27-2 3-(Methoxymethyl)-2-methylbenzaldehyde 
• 247575-30-0 1,2-bis(3'-cyano-2'-methylphenyl)ethane 
• 247575-31-1 1,2-bis(3'-formyl-2'-methylphenyl)ethane 
• 247575-29-7 1,2-bis(3'-chloro-2'-methylphenyl)ethane 

Relevant academic research and scientific papers

Enantioselective Intermolecular C-H Amination Directed by a Chiral Cation

The enantioselective amination of C(sp3)-H bonds is a powerful synthetic transformation yet highly challenging to achieve in an intermolecular sense. We have developed a family of anionic variants of the best-in-class catalyst for Rh-catalyzed C-H amination, Rh2(esp)2, with which we have associated chiral cations derived from quaternized cinchona alkaloids. These ion-paired catalysts enable high levels of enantioselectivity to be achieved in the benzylic C-H amination of substrates bearing pendant hydroxyl groups. Additionally, the quinoline of the chiral cation appears to engage in axial ligation to the rhodium complex, providing improved yields of product versus Rh2(esp)2 and highlighting the dual role that the cation is playing. These results underline the potential of using chiral cations to control enantioselectivity in challenging transition-metal-catalyzed transformations.

3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF

The present invention provides compounds, compositions thereof, and methods of using the same.

Amine compound and a manufacturing method thereof, and use thereof

PROBLEM TO BE SOLVED: To provide a material for an organic EL developing a higher efficiency than conventional materials, and a material very useful particularly in an organic EL device using a phosphorescent material. SOLUTION: The material is an a

TETRAHYDROISOQUINOLINE COMPOUND

The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.

THIAZOLOPYRIMIDINONE DERIVATIVES AS PI3 KINASE INHIBITORS

This invention relates to the use of thiazolopyrimidinone derivatives for the modulation, notably the inhibition of the activity or function of the phosphoinositide 3' OH kinase family (hereinafter PI3 kinases), suitably, PI3Kα, PI3Kδ, PI3Kβ, and/or PI3Kγ

Rational modification of a candidate cancer drug for use against chagas disease

Chagas disease is one of the major neglected diseases of the world. Existing drug therapies are limited, ineffective, and highly toxic. We describe a novel strategy of drug discovery of adapting an existing clinical compound with excellent pharmaceutical properties to target a pathogenic organism. The protein farnesyltransferase (PFT) inhibitor tipifarnib, now in phase III anticancer clinical trials, was previously found to kill Trypanosoma cruzi by blocking sterol 14a-demethylase (14DM). We rationally developed tipifarnib analogues that display reduced affinity for human PFT to reduce toxicity while increasing affinity for parasite 14DM. The lead compound has picomolar activity against cultured T. cruzi and is efficacious in a mouse model of acute Chagas disease.

ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS

The invention provides well-defined aryl fluoroethyl ureas that are useful as selective alpha2 adrenergic agonists. As such, the compounds described herein are useful in treating a wide variety of disorders associated with modulation of alpha2 adrenergic receptors.

INHIBITORS OF MONOAMINE UPTAKE

N,N-disubstituted 4-amino-piperidines of the general Formula (I) are inhibitors of the uptake of serotonin and/or norepinephrine and/or dopamine. As such, they may be useful for the treatment of disorders of the central and/or peripheral nervous system.

Syntheses and Reactions of the First Dithiametacyclophanes, Metacyclophanes, and Metacyclophanedienes

Two new cyclophane series, the dithiametacyclophanes 5 and the metacyclophanedienes 6, are synthesized and their chemistry is described.On the basis of this chemistry, such cyclophanes appear not to adopt the syn or anti conformations fo