90381-85-4Relevant academic research and scientific papers
Stereochemistry in the Knoevenagel Reaction of Methyl Arylsulphinylacetate and Aldehydes
Tanikaga, Rikuhei,Konya, Naoto,Tamura, Tadashi,Kaji, Aritsune
, p. 825 - 830 (2007/10/02)
The stereochemistry of the mechanism of the amine-catalyzed Knoevenagel reaction has been studied.Simple treatment of methyl arylsulphinylacetate (1) and aldehydes (2) with a catalytic amount of a secondary amine produced thermodynamically stable E-alkene
STEREOCHEMISTRY OF AMINE-CATALYZED KNOEVENAGEL REACTIONS
Tanikaga, Rikuhei,Konya, Naoto,Kaji, Aritsune
, p. 1583 - 1586 (2007/10/02)
The amine-catalyzed Knoevenagel reactions of aldehydes and active methylene compounds containing two activating groups were found to involve many reversible steps, and the diastereomeric intermediary condensation compounds yielded thermodynamically stable products via carbanionic intermediates stablized and sterically affected by two activating groups.
Selective Synthesis of α-Sulphenyl-, α-Sulphinyl-, and α-Sulphonyl-α,β-unsaturated Carbonyl Compounds by the Knoevenagel Reaction
Tanikaga, Rikuhei,Tamura, Tadashi,Nozaki, Yoshihito,Kaji, Aritsune
, p. 87 - 88 (2007/10/02)
Simple treatment of aldehydes with the carbonyl compounds (1) 2COCH2S(O)nAr; n = 0, 1, 2> and piperidine stereoselectively produces the condensation products (7), the stereochemistry of which is controlled by the steric requirements of two fu
