90390-21-9

Usage

Uses

Used in Household and Industrial Cleaning Products:
N-methyl-3,5-dichlorobenzylamine is utilized as a disinfectant and antimicrobial agent in various cleaning products. Its strong antibacterial properties allow it to effectively eliminate a broad spectrum of bacteria, fungi, and viruses, ensuring a hygienic and clean environment.
Used in Healthcare Settings:
In the healthcare industry, N-methyl-3,5-dichlorobenzylamine is employed for disinfection and sterilization purposes. Its effectiveness against a wide range of pathogens makes it a crucial component in maintaining a sterile environment, thus preventing the spread of infections and promoting patient safety.
Used in Sanitation and Hygiene Applications:
Beyond household and industrial cleaning, N-methyl-3,5-dichlorobenzylamine is also applied in broader sanitation and hygiene applications. Its versatility in combating various microorganisms makes it a commonly used chemical for ensuring cleanliness and reducing the risk of disease transmission in various settings.

Upstream product

• 10203-08-4 3,5-dichlorobenzaldehyde 
• 74-89-5 methylamine 

Relevant academic research and scientific papers

Tertiary Amine Pyrazolones and Their Salts as Inhibitors of Mutant Superoxide Dismutase 1-Dependent Protein Aggregation for the Treatment of Amyotrophic Lateral Sclerosis

Pyrazolone derivatives have previously been found to be inhibitors of Cu/Zn superoxide dismutase 1 (SOD1)-dependent protein aggregation, which extended survival of an amyotrophic lateral sclerosis (ALS) mouse model. On the basis of ADME analysis, we describe herein a new series of tertiary amine-containing pyrazolones and their structure-activity relationships. Further conversion to the conjugate salts greatly improved their solubility. Phosphate compound 17 exhibited numerous benefits both to cellular activity and to CNS-related drug-like properties in vitro and in vivo, including microsomal stability, tolerated toxicity, and blood-brain barrier permeation. These results indicate that tertiary amine pyrazolones comprise a valuable class of ALS drug candidates.

TACHYKININ RECEPTOR ANTAGONISTS

The present invention relates to selective NK-1 receptor antagonists of Formula (I) or a pharmaceutically acceptable salt thereof, for the treatment of disorders associated with an excess of tachykinins.

Benzylamines: Synthesis and evaluation of antimycobacterial properties

The synthesis of benzylamines with various N-alkyl chains and substituents in the aromatic system as well as their evaluation on Mycobacterium tuberculosis H 37 Ra are described. The most active compounds in this test, N-methyl-3-chlorobenzylamine (MIC 10.2 μg/mL), N-methyl-3,5-dichlorobenzylamine (93, MIC 10.2 μg/mL), and N-butyl-3,5-difluorobenzylamine (MIC 6.4 μg/mL), also exhibited a marked inhibitory effect on Mycobacterium marinum and Mycobacterium lufu used for the determination of antileprotic properties. The combination of 93 with aminosalicylic acid, streptomycin, or dapsone exert marked supra-additive effects on M. tuberculosis H 37 Ra.