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2-bromo-3-methoxy-1,3-diphenylpropan-1-one is an organic compound with the molecular formula C16H15BrO2. It is a derivative of 1,3-diphenylpropan-1-one, featuring a bromine atom at the 2-position and a methoxy group at the 3-position. This chemical is characterized by its aromatic structure, with two phenyl rings attached to a propanoic ketone backbone. The presence of the bromine atom and methoxy group imparts unique chemical properties to the molecule, such as increased reactivity and solubility in polar solvents. 2-bromo-3-methoxy-1,3-diphenylpropan-1-one may be used in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals due to its versatile structure and functional groups.

90399-66-9

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90399-66-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 90399-66-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,3,9 and 9 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 90399-66:
(7*9)+(6*0)+(5*3)+(4*9)+(3*9)+(2*6)+(1*6)=159
159 % 10 = 9
So 90399-66-9 is a valid CAS Registry Number.

90399-66-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-3-methoxy-1,3-diphenylpropan-1-one

1.2 Other means of identification

Product number -
Other names R,R-S,S-2-Brom-3-methoxy-1-phenyl-3-phenylpropanon

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90399-66-9 SDS

90399-66-9Relevant academic research and scientific papers

Oxidation of α,β-Unsaturated Ketones by Organophotocatalysis Using Rhodamine 6G under Visible Light Irradiation: Insight into the Reaction Mechanism

Yoshioka, Eito,Takahashi, Hiroki,Wanibe, Hikari,Hontani, Yukina,Hatsuse, Kouki,Shimizu, Remi,Kawashima, Akira,Kohtani, Shigeru,Miyabe, Hideto

, p. 697 - 704 (2021/11/13)

The oxidative transformation of α,β-unsaturated ketones was investigated under visible-light-induced photocatalytic conditions using rhodamine 6G as an organophotocatalyst. In this organocatalysis, the mild co-oxidant bromotrichloromethane (BrCCl3) acts n

Catalytic asymmetric intra- and intermolecular haloetherification of enones: An efficient approach to (?)-Centrolobine

Zhou, Pengfei,Cai, Yunfei,Zhong, Xia,Luo, Weiwei,Kang, Tengfei,Li, Jun,Liu, Xiaohua,Lin, Lili,Feng, Xiaoming

, p. 7778 - 7783 (2018/05/23)

A catalytic asymmetric intra- and intermolecular haloetherification of electron-deficient alkenes (halogen = Cl, Br, I) has been realized by the use of chiral metal complexes of N,N′-dioxides. In the presence of a chiral Fe(III) complex, a series of tetrahydropyran derivatives were obtained in good yields (up to 99% yield) with a high level of enantioselectivities (up to 97% ee). Promoted by a chiral Ce(III) complex, chiral oxepane derivatives could be given in good results. Moreover, the intermolecular haloetherification of chalcones catalyzed by Sc(III) complex using MeOH as nucleophile is demonstrated. This methodology also can be successfully applied to the synthesis of (?)-Centrolobine. Meanwhile, a reasonable reaction mechanism was proposed.

Alkoxybromination of olefins using ammonium bromide and oxone

Kumar, Macharla Arun,Naresh, Mameda,Rohitha, Chozhiyath Nappunni,Narender, Nama

supporting information, p. 3121 - 3129 (2014/01/06)

A mild, efficient, and highly regio- and stereoselective method for the methoxy and ethoxy bromination of olefins has been developed using NH 4Br as a bromine source and Oxone as an oxidant. Various kinds of olefins (aromatic, linear, and cyclic olefins) afforded the corresponding alkoxy brominated products in moderate to excellent yields. Taylor & Francis Group, LLC.

[Cu(dap)2Cl] as an efficient visible-light-driven photoredox catalyst in carbon-carbon bond-forming reactions

Pirtsch, Michael,Paria, Suva,Matsuno, Taisuke,Isobe, Hiroyuki,Reiser, Oliver

supporting information; experimental part, p. 7336 - 7340 (2012/09/08)

Copper sees the light of day: [Cu(dap)2Cl] proved to be an excellent photoredox catalyst for atom-transfer radical addition reactions, as well as for allylation reactions (see scheme), providing an attractive alternative to commonly used iridium- and ruthenium-based catalysts. Copyright

A regioselective and stereoselective methoxy bromination of olefins using diacetoxyiodobenzene and phenyltrimethyl ammoniumtribromide

Hangirgekar,Shirodkar

experimental part, p. 179 - 184 (2012/01/13)

A facile regio and stereoselective methoxy-bromination of alkenes using phenyltrimethyl ammoniumtribromide (PTAB) and (diacetoxyiodo) benzene (DIB) as oxidant has been carried out in the present investigation. The IR, NMR and LCMS of all the synthesized compounds have been used to characterize them.

Organocatalysis in the stereoselective bromohydrin reaction of alkenes

Bar, Sukanta

experimental part, p. 605 - 612 (2010/08/21)

An efficient regio- and stereo-selective (>99:1) trans-bromohydrination (bromohydroxylation and bromomethoxylation) of alkenes including α,β-unsaturated carbonyl compounds with N-bromosuccinimide (NBS) has been achieved by using 1.0 mol% of N,N'-diarylthi

Comparative study of the vicinal functionalization of olefins with 2:1 bromide/bromate and iodide/iodate reagents

Agrawal, Manoj K.,Adimurthy, Subbarayappa,Ganguly, Bishwajit,Ghosh, Pushpito K.

experimental part, p. 2791 - 2797 (2009/08/08)

A comparative evaluation was made on the syntheses of vicinal halohydrins, halo methyl ethers, and halo acetates from olefins using 2:1 Br-/BrO3- and I-/IO3- reagents. In many cases both reagents afforded products selectively in high yields. The highest halogen atom efficiencies attained were 97% and 93% for Br-/BrO3- and I-/IO3-, respectively. Of the two reagents, I-/IO3- was established to be the preferred reagent for vicinal functionalization of linear alkenes and also for halo acetate preparation. However, only Br-/BrO3- was effective for vicinal functionalization of trans-stilbene and chalcones.

Action of tetrabutylammonium tribromide with para-substituted chalcones in protic and aprotic media

Berthelot, Jacques,Benammar,Yamina,Desmazieres, Bernard

, p. 1526 - 1530 (2007/10/03)

Bromination of the double bond of para-substituted chalcones under mild conditions in aprotic solvents is accomplished with high yields using tetrabutylammonium tribromide (TBABr3).In methanol, the main reaction is (α-β) bromoethoxylation.Stereoselectivity, regioselectivity, and chemioselectivity of this bromomethoxylation reaction are described.Key words: bromination, bromoethoxylation, tetrabutylammonium tribromide, (α-β) dibromodihydrochalcones, α-bromo-β-methoxydihydrochalcones.

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