904326-87-0

Basic information

• Product Name: 2-ACETAMIDOPYRIDINE-5-BORONIC ACID PINACOL ESTER, 97%
• Synonyms: N-[5-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridin-2-yl]-acetamide;[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridyl]acetamide;N-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridyl]acetamide;2-Acetamidopyridine-5-boronic acid pinacol ester;6-Acetamidopyridine-3-boronic acid pinacol ester;6-(Acetylamino)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 6-(Acetylamino)pyridine-3-boronic acid, pinacol ester;2-(Acetylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine, 6-(Acetylamino)pyridine-3-boronic acid, pinacol ester;[2-ACETAMIDOPYRIDINE-5-BORONIC ACID PINACOL ESTER, 97%]
• CAS NO: 904326-87-0
• Molecular Formula: C₁₃H₁₉BN₂O₃
• Molecular Weight: 262.11256
• EINECS: 200-528-9
• Product Categories: Boronate Esters;Boronic Acids and Derivatives;Chemical Synthesis;Heteroaryl Boronate Esters;Organometallic Reagents
• Mol File: 904326-87-0.mol
• Article Data: 14

Chemical Properties

• Melting Point: 130-134 °C
• Boiling Point: 444.4°C at 760 mmHg
• Flash Point: 222.5ºC
• Appearance: /
• Density: 1.11g/cm3
• Vapor Pressure: 4.31E-08mmHg at 25°C
• Refractive Index: 1.509
• Storage Temp.: 2-8°C
• PKA: 13.95±0.70(Predicted)
• CAS DataBase Reference: 2-ACETAMIDOPYRIDINE-5-BORONIC ACID PINACOL ESTER, 97%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-ACETAMIDOPYRIDINE-5-BORONIC ACID PINACOL ESTER, 97%(904326-87-0)
• EPA Substance Registry System: 2-ACETAMIDOPYRIDINE-5-BORONIC ACID PINACOL ESTER, 97%(904326-87-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 904326-87-0(Hazardous Substances Data)

Usage

Uses

2-Acetamidopyridine-5-boronic Acid Pinacol Ester, is a reagent used to synthesize new quinolinequinone derivatives as cytotoxic agents. In addition, novel benzoxazinyl-oxazolidinones are synthesized using this compound with application towards antibacterial agents.

InChI:InChI=1/C13H19BN2O3/c1-9(17)16-11-7-6-10(8-15-11)14-18-12(2,3)13(4,5)19-14/h6-8H,1-5H3,(H,15,16,17)

Upstream product

• 827614-64-2 2-aminopyridine-5-boronic acid pinacol ester 
• 108-24-7 acetic anhydride 
• 142404-84-0 N-(5-bromo-6-methyl-pyridin-2-yl)-acetamide 
• 73183-34-3 bis(pinacol)diborane 
• 7169-97-3 N-(5-bromopyridin-2-yl)acetamide 
• 25015-63-8 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane 
• 1072-97-5 5-bromo-2-pyridylamine 

Downstream Products

• 1332448-72-2 5-(2-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)-N-methylpicolinamide 
• 1332448-95-9 N-(5-(2-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)pyridin-2-yl)acetamide 
• 1332448-20-0 N-(5-(3-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)pyridin-2-yl)acetamide 
• 1332448-80-2 5-(3-(2,8-dimethyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)phenyl)-N-methylpicolinamide 
• 1415999-92-6 N-(5-(9-oxo-10-(3-(trifluoromethyl)phenyl)-9,10-dihydropyrido[3,2-c][1,5]naphthyridin-2-yl) pyridin-2-yl)acetamide 
• 1613168-67-4 2-{[4-(6-acetamidopyridin-3-yl)phenyl]amino}-N-[4-(piperazin-1-ylmethyl)-3-(trifluoromethyl)phenyl]acetamide 
• 1613168-50-5 2-{[4-(6-acetamidopyridin-3-yl)phenyl]amino}-N-{4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}acetamide 
• 1251949-00-4 N-(5-(7-chloro-3-(2-chlorobenzyl)-1-(4-methoxybenzyl)-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl)pyridin-2-yl)acetamide 

Relevant articles and documents

PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS

The present disclosure provides selective phosphoinositide 3-kinase gamma inhibitors of Formula (I) including (I-a), (I-b), (I-c), and (I-d), or pharmaceutically acceptable salts thereof. These compounds are useful for the treatment of conditions mediated

A 2-amino-thiazole compounds (by machine translation)

The present invention relates to the technical field of pharmaceutical chemistry, particularly relates to a 2-amino thiazole compound or its pharmaceutically acceptable salts, its preparation method, and pharmaceutical compositions containing such compounds and its application in the preparation of antineoplastic. (by machine translation)

PHOSPHOINOSITIDE 3-KINASE INHIBITORS WITH ZINC BINDING MOIETY

PROBLEM TO BE SOLVED: To provide phosphoinositide 3-kinase inhibitors with a zinc binding moiety. SOLUTION: There is provided a compound represented by formula (I) in the figure. (X is S, O or the like; Y is CH, N or the like; G1 is optionally substituted N or the like; R1 and R2 are each independently H or the like; C is a substituted heterocycle or the like; B is a linear alkyl or the like; Ra and Rb together with the nitrogen atom coupled to them are morpholino or the like; G2 is an indazole ring or the like; q, r and s are independently from 0 to 1, provided that at least one of them is 1; t is from 0 to 1; n is from 0 to 4; and p is from 0 to 2.) COPYRIGHT: (C)2016,JPOandINPIT