90481-72-4Relevant articles and documents
The total synthesis of (?)-indolactam I
Mendoza, Manuel,Rao, Niveda,Tran, UyenPhuong,Castaneda, Catherine,Billingsley, Kelvin L.
, p. 4337 - 4342 (2019)
The first total synthesis of (?)-indolactam I (1) is reported. An efficient synthetic route was established to furnish the natural product in 8 steps. This strategy employed a copper-catalyzed amino acid arylation, peptide coupling, and Lewis acid-mediate
Rhodium(II)-Catalyzed [4+3] Cyclization of Triazoles with Indole Derivatives and Its Application in the Total Synthesis of (±)-Aurantioclavine
Duan, Shengguo,Xue, Bing,Meng, Hui,Ye, Zihang,Xu, Ze-Feng,Li, Chuan-Ying
supporting information, p. 1145 - 1152 (2021/04/26)
An efficient rhodium(II)-catalyzed [4+3] cyclization reaction of 1-sulfonyl-1,2-3-triazoles and indoles was developed. Azepino[5,4,3- cd]indoles, which are widely distributed in ergot alkaloids with various biological activities, could be obtained in good
The Synthesis and Biological Evaluation of Indolactam Alkaloids
Billingsley, Kelvin L.,Eom, Ryan,Haynes-Smith, Jeremy,Mendoza, Manuel,Salas, Celeste
, p. 4443 - 4451 (2019/11/21)
In this work, we execute a general synthetic strategy to access novel indolactam alkaloids, which are agonists of protein kinase C. This protocol allowed for the most efficient reported syntheses of indolactam V (ILV) stereoisomers, while also affording t