904929-91-5

Upstream product

• 103483-32-5 1-iodo-6-(tert-butyldimethylsiloxy)hexane 
• 620-08-6 4-methoxypyridine 
• 87768-46-5 N-[(1S)-1-(methoxymethyl)-2-methylpropyl]benzamide 

Downstream Products

• 904930-00-3 2-[6-(tert-butyl-dimethyl-silanyloxy)-hexyl]-5-iodo-1-[(1-methoxymethyl-2-methyl-propylimino)-phenyl-methyl]-2,3-dihydro-1H-pyridin-4-one 
• 904929-79-9 (2R)-2-hept-6-enyl-5-iodo-1-((E)-{((1S)-1-(methoxymethyl)-2-methylpropyl)imino}(phenyl)methyl)-4-oxo-2,3-dihydropyridin-4(1H)-one 
• 904930-02-5 6-{(2R)-5-iodo-1-((E)-{((1S)-1-(methoxymethyl)-2-methylpropyl)imino}(phenyl)methyl)-4-oxo-1,2,3,4-tetrahydropyridin-2-yl}hexanal 
• 904930-01-4 (2R)-2-(6-hydroxyhexyl)-5-iodo-1-((E)-{((1S)-1-(methoxymethyl)-2-methylpropyl)imino}(phenyl)methyl)-2,3-dihydropyridin-4(1H)-one 
• 904930-03-6 tert-butyl (6R)-6-hept-1-((E)-{((1S)-1-(methoxymethyl)-2-methylpropyl)imino}(phenyl)methyl)-4-oxo-1,4,5,6-tetrahydropyridin-3-ylcarbamate 

Relevant academic research and scientific papers

Stereoselective synthesis of pyridinones: Application to the synthesis of (-)-barrenazines

The stereoselective synthesis of pyridinones was accomplished by the nucleophilic addition of Grignard reagents to a chiral pyridinium salt derived from 4-methoxypyridine. This methodology was applied to an expedient synthesis of (-)-barrenazine A and B.