90525-99-8

Basic information

• Product Name: Benzamide, N,N,2,3-tetramethyl-
• CAS NO: 90525-99-8
• Molecular Formula: C11H15NO
• Molecular Weight: 177.246
• Mol File: 90525-99-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N,2,3-tetramethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N,2,3-tetramethyl-(90525-99-8)
• EPA Substance Registry System: Benzamide, N,N,2,3-tetramethyl-(90525-99-8)

Safety Data

• Hazardous Substances Data: 90525-99-8(Hazardous Substances Data)

Upstream product

• 21900-46-9 2,3-dimethylbenzoyl chloride 
• 124-40-3 dimethyl amine 
• 603-79-2 2,3-dimethylbenzoic acid 
• 13360-57-1 dimethylamino sulfonyl chloride 
• 78162-58-0 N,N-dimethyl-1H-imidazole-1-sulfonamide 

Downstream Products

• 1613436-03-5 4,5-dimethyl-3-phenylisoquinolin-1(2H)-one 
• 1260150-57-9 5-methyl-3-phenylisoquinolin-1(2H)-one 
• 1560949-11-2 5-methyl-3-(4-methylphenyl)isoquinolin-1-one 
• 1613435-52-1 3-(4-chlorophenyl)-5-methylisoquinolin-1(2H)-one 
• 1613435-53-2 5-methyl-3-(4-trifluoromethylphenyl)isoquinolin-1(2H)-one 
• 1613435-54-3 3-(2-chlorophenyl)-5-methylisoquinolin-1(2H)-one 
• 1613435-55-4 3-(3-chlorophenyl)-5-methylisoquinolin-1(2H)-one 
• 1613435-56-5 3-(2,6-dichlorophenyl)-5-methylisoquinolin-1(2H)-one 
• 1454901-02-0 3-(4-bromophenyl)-5-methyl-2H-isoquinolin-1-one 
• 1613435-58-7 5-methyl-3-(4-phenylethynylphenyl)isoquinolin-1(2H)-one 
• 1369949-88-1 2-ethyl-N,N,3-trimethylbenzamide 
• 1454898-07-7 5-methyl-3-(4-(pyrrolidin-1-ylmethyl)phenyl)isoquinolin-1(2H)-one 
• 1454898-09-9 5-methyl-3-(4-(piperidin-1-ylmethyl)phenyl)isoquinolin-1-one 
• 1613436-05-7 3-(4-(1,1-dimethylethyl)phenyl)-5-methylisoquinolin-1(2H)-one 

Relevant articles and documents

A novel method for the one-pot conversion of carboxylic acids to N,N-dimethylamides

A simple, efficient, and new method has been developed for the preparation of N,N-dimethylamides from carboxylic acids. As described below, treatment of a variety of aromatic carboxylic acids with N,N-dimethylsulfamoyl imidazole or N,N-dimethylsulfamoyl chloride in the presence of a mixture of methanesulfonic acid/phosphorus pentoxide (2:1, v/w) proceeded effectively to afford the corresponding N,N-dimethylamides inmoderate to good yields. Thismethod is easy, rapid, and good yielding for the synthesis of N,N-dimethylamides from carboxylic acids. Iranian Chemical Society 2012.

TANKYRASE INHIBITORS

The present invention relates to a compound of formula I wherein X is C(R6) or N, Y is C or N, and ring A, ring B, R1 and R2 have the meanings defined herein, provided that when ring B is carbocyclic, X is C(R6); or a pharmaceutically acceptable salt or solvate thereof. The compounds are tankyrase-1 and tankyrase-2 inhibitors and are useful in the treatment of a number of conditions, including cancer.