90532-02-8

Basic information

• Product Name: (4-Bromo-3-methylphenyl)(methyl)sulphane
• Synonyms: (4-Bromo-3-methylphenyl)(methyl)sulphane;4-Bromo-3-methylthioanisole;(4-Bromo-3-methylphenyl)(methyl)sulfane;1-Bromo-2-methyl-4-(methylsulphanyl)benzene, 4-Bromo-3-methylphenyl methyl sulphide, 2-Bromo-5-(methylthio)toluene;1-Bromo-2-methyl-4-(methylthio)benzene
• CAS NO: 90532-02-8
• Molecular Formula: C₈H₉BrS
• Molecular Weight: 217.13
• Product Categories: blocks;Bromides
• Mol File: 90532-02-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 254.9°Cat760mmHg
• Flash Point: 108°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 0.0269mmHg at 25°C
• Refractive Index: 1.608
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (4-Bromo-3-methylphenyl)(methyl)sulphane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Bromo-3-methylphenyl)(methyl)sulphane(90532-02-8)
• EPA Substance Registry System: (4-Bromo-3-methylphenyl)(methyl)sulphane(90532-02-8)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 90532-02-8(Hazardous Substances Data)

Usage

General Description

The chemical compound (4-Bromo-3-methylphenyl)(methyl)sulphane is an organosulphur compound with a molecular formula C8H9BrS. It consists of a benzene ring with a methyl group and a bromine atom attached, as well as a methylsulphane group. (4-Bromo-3-methylphenyl)(methyl)sulphane is commonly used in organic chemistry as a reagent for various reactions, including the synthesis of other organosulphur compounds. It is also known for its potential pharmaceutical and biological applications due to its unique chemical properties. Additionally, (4-Bromo-3-methylphenyl)(methyl)sulphane is considered to be a stable and relatively safe compound when handled and stored properly.

InChI:InChI=1/C8H9BrS/c1-6-5-7(10-2)3-4-8(6)9/h3-5H,1-2H3

Upstream product

• 4886-77-5 3-methylthioanisole 
• 452-63-1 2-Bromo-5-fluorotoluene 
• 5188-07-8 sodium thiomethoxide 
• 108-40-7 toluene-3-thiol 
• 14395-52-9 3-methyl-4-bromothiophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 99769-28-5 1-bromo-2-methyl-4-(methylsulfonyl)benzene 
• 444722-03-6 2-methyl-4-(methylsulfanyl)phenylboronic acid 
• 1127563-79-4 2-methyl-4-(methylsulfinyl)phenyl bromide 
• 1610372-71-8 2-(5-(2-(isopropylamino)ethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)pyridin-2-yl)-5,7-dimethoxyquinazolin-4(3H)-one 
• 1610373-51-7 2-[5-(2-bromo-ethoxy)-6-(4-methanesulfonyl-2-methyl-phenyl)-pyridin-2-yl]-5,7-dimethoxy-3H-quinazolin-4-one 
• 1610372-65-0 2-(5-(2-hydroxyethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)pyridin-2-yl)-5,7-dimethoxyquinazolin-4(3H)-one 
• 1610373-36-8 5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)picolinaldehyde 
• 1011459-26-9 4,4,5,5-tetramethyl-2-(2-methyl-4-(methylsulfonyl)phenyl)-1,3,2-dioxaborolane 
• 1382136-48-2 4-[5-(2-methyl-4-methylsulfanyl-phenyl)-2,3-dihydro-benzofuran-2-yl]-piperidine-1-carboxylic acid isopropyl ester 
• 1380646-57-0 3-(4-fluorophenyl)-2-(4-methanesulfonyl-2-methyl-phenyl)-propionic acid 
• 1380646-56-9 3-(4-fluorophenyl)-2-(2-methyl-4-methylsulfanyl-phenyl)-propionic acid tert-butyl ester 
• 1380646-03-6 N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-2-methyl-phenyl)-propionamide 
• 1380646-55-8 (2-methyl-4-methylsulfanylphenyl)-acetic acid tert-butyl ester 

Relevant articles and documents

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

PRC2 INHIBITORS

The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))

IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R3, R4, R6, and R7 are as defined herein.