90532-02-8

Usage

Uses

Used in Organic Chemistry:
(4-Bromo-3-methylphenyl)(methyl)sulphane is used as a reagent in organic chemistry for [various reactions] because of [its unique chemical properties that facilitate the synthesis of other organosulphur compounds].
Used in Pharmaceutical and Biological Applications:
In the pharmaceutical and biological sectors, (4-Bromo-3-methylphenyl)(methyl)sulphane is used as a compound with [potential applications] due to [its distinctive chemical properties that may offer benefits in drug development and biological research].
Used in Chemical Synthesis:
(4-Bromo-3-methylphenyl)(methyl)sulphane is used as a starting material or intermediate in chemical synthesis for [the production of specific organosulphur compounds] because of [its structural features that allow for further chemical modifications and reactions].

InChI:InChI=1/C8H9BrS/c1-6-5-7(10-2)3-4-8(6)9/h3-5H,1-2H3

Upstream product

• 452-63-1 2-Bromo-5-fluorotoluene 
• 5188-07-8 sodium thiomethoxide 
• 108-40-7 toluene-3-thiol 
• 4886-77-5 3-methylthioanisole 
• 14395-52-9 3-methyl-4-bromothiophenol 
• 74-88-4 methyl iodide 

Downstream Products

• 99769-28-5 1-bromo-2-methyl-4-(methylsulfonyl)benzene 
• 444722-03-6 2-methyl-4-(methylsulfanyl)phenylboronic acid 
• 1127563-79-4 2-methyl-4-(methylsulfinyl)phenyl bromide 
• 1610372-71-8 2-(5-(2-(isopropylamino)ethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)pyridin-2-yl)-5,7-dimethoxyquinazolin-4(3H)-one 
• 1610373-51-7 2-[5-(2-bromo-ethoxy)-6-(4-methanesulfonyl-2-methyl-phenyl)-pyridin-2-yl]-5,7-dimethoxy-3H-quinazolin-4-one 
• 1610372-65-0 2-(5-(2-hydroxyethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)pyridin-2-yl)-5,7-dimethoxyquinazolin-4(3H)-one 
• 1610373-36-8 5-(2-((tert-butyldimethylsilyl)oxy)ethoxy)-6-(2-methyl-4-(methylsulfonyl)phenyl)picolinaldehyde 
• 1011459-26-9 4,4,5,5-tetramethyl-2-(2-methyl-4-(methylsulfonyl)phenyl)-1,3,2-dioxaborolane 
• 1382136-48-2 4-[5-(2-methyl-4-methylsulfanyl-phenyl)-2,3-dihydro-benzofuran-2-yl]-piperidine-1-carboxylic acid isopropyl ester 
• 1380646-57-0 3-(4-fluorophenyl)-2-(4-methanesulfonyl-2-methyl-phenyl)-propionic acid 
• 1380646-56-9 3-(4-fluorophenyl)-2-(2-methyl-4-methylsulfanyl-phenyl)-propionic acid tert-butyl ester 
• 1380646-03-6 N-Benzooxazol-2-yl-3-(4-fluoro-phenyl)-2-(4-methanesulfonyl-2-methyl-phenyl)-propionamide 
• 1380646-55-8 (2-methyl-4-methylsulfanylphenyl)-acetic acid tert-butyl ester 

Relevant academic research and scientific papers

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

IMIDAZO[1,2-C]PYRIMIDINE DERIVATIVES AS PRC2 INHIBITORS FOR TREATING CANCER

Disclosed are compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, disclosed are compounds of Formula (I) and pharmaceutical compositions thereof, and methods of using the compounds and pharmaceutical compositions in, for example, methods of treating cancer.

PRC2 INHIBITORS

The present invention relates to compounds that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention. (Formula (I))

Environmentally benign indole-catalyzed position-selective halogenation of thioarenes and other aromatics

Halogenated aromatic compounds are the cores of many pharmaceutical, agricultural and chemical products but they are commonly prepared using electrophilic halogenation reactions in non-green chlorinated solvents under harsh conditions. A separate problem happens in the aromatic halogenation of thioarenes because they readily undergo oxidative side-reactions. Herein we report an environmentally benign electrophilic bromination of aromatics using an indole-catalytic protocol, which is suitable for a wide range of substrates including thioarenes.

IMIDAZOPYRIMIDINE COMPOUNDS USEFUL FOR THE TREATMENT OF CANCER

A compound of Formula (IA), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein A, R3, R4, R6, and R7 are as defined herein.

TRIAZOLOPYRIMIDINE COMPOUNDS AND USES THEREOF

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is provided that has been shown to be useful for treating a PRC2-mediated disease or disorder: wherein R1, R2, R3, R4, R5, and n are as defined herein.

NAPHTHYLACETIC ACIDS

The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

BICYCLIC COMPOUNDS AND USE AS ANTIDIABETICS

The present invention relates to novel compounds that are useful in the treatment of metabolic disorders, particularly type II diabetes mellitus and related disorders, and also to the methods for the making and use of such compounds.

PHTHALAZINE, AZA- AND DIAZA-PHTHALAZINE COMPOUNDS AND METHODS OF USE

The present invention comprises a new class of compounds useful for the prophylaxis and treatment of protein kinase mediated diseases, including inflammation and related conditions. The compounds have a general Formula I wherein A1, A2/su