905458-50-6

Upstream product

• 10067-33-1 (S)-(-)-p-mentha-1,8⁽¹⁰⁾-dien-9-ol 
• 5989-54-8 (-)-(S)-limonene 
• 33821-94-2 3-(tetrahydro-2H-pyran-2-yloxy)propyl bromide 
• 636603-07-1 8-(tert-butyl-dimethyl-silanyloxymethyl)-5-[1-(tert-butyl-diphenyl-silanyloxymethyl)-vinyl]-12-methyl-15-(tetrahydro-pyran-2-yloxy)-pentadeca-7,11-dien-2-ol 
• 636603-05-9 6-(tert-butyl-diphenyl-silanyloxymethyl)-2-[4-methyl-7-(tetrahydro-pyran-2-yloxy)-hept-3-enyl]-5-(3-oxo-butyl)-hepta-2,6-dienoic acid ethyl ester 

Downstream Products

• 636603-07-1 8-(tert-butyl-dimethyl-silanyloxymethyl)-5-[1-(tert-butyl-diphenyl-silanyloxymethyl)-vinyl]-12-methyl-15-(tetrahydro-pyran-2-yloxy)-pentadeca-7,11-dien-2-ol 
• 636603-04-8 8-(tert-butyl-dimethyl-silanyloxymethyl)-12-(tert-butyl-diphenyl-silanyloxymethyl)-4-methyl-11-(3-oxo-butyl)-trideca-4,8,12-trienal 
• 636603-08-2 (1E,5E,9Z)-(S)-9-(tert-Butyl-dimethyl-silanyloxymethyl)-12-[1-(tert-butyl-diphenyl-silanyloxymethyl)-vinyl]-1,5-dimethyl-cyclotetradeca-1,5,9-triene 
• 1027188-45-9 {(4E,8E)-(1S,12S,14R)-12-[1-(tert-Butyl-diphenyl-silanyloxymethyl)-vinyl]-5,9-dimethyl-15-oxa-bicyclo[12.1.0]pentadeca-4,8-dien-1-yl}-methanol 
• 636603-10-6 tert-Butyl-diphenyl-[2-((6E,10E)-(1R,3S,14R)-6,10,14-trimethyl-15-oxa-bicyclo[12.1.0]pentadeca-6,10-dien-3-yl)-allyloxy]-silane 
• 148149-83-1 pseudoplexaurol 

Relevant academic research and scientific papers

A mild and efficient desilylation of O-tert-butyldimethylsilyl ethers mediated by chlorotrimethylsilane and potassium fluoride dihydrate in acetonitrile

Desilylation of O-tert-butyldimethylsilyl ethers was achieved by a reagent system consisting of chlorotrimethylsilane and potassium fluoride dihydrate in acetonitrile. This alternative desilylation procedure is chemoselective, generally effective and operationally simple, and should find practical applications in organic synthesis. Georg Thieme Verlag Stuttgart.

Asymmetric Total Synthesis of Pseudoplexaurol and 14-Deoxycrassin, two Antitumor Marine Cembrane Diterpenoids

The first asymmetric total synthesis of two naturally occurring antitumor pseudoplexaurol and 14-deoxycrassin were achieved via two convergent synthetic sequences featured a chiral pool protocol to implement C-1 stereogenic center and Ti(0)-mediated cyclization leading to cembrane ring.