90560-52-4

Upstream product

• 77344-70-8 1-(2-bromo-5-methylphenyl)ethanone 
• 824-54-4 2-bromo-4-methylbenzaldehyde 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 42872-83-3 2-bromo-5-methylbenzylnitrile 
• 620-22-4 3-Methylbenzonitrile 
• 90221-55-9 2-bromo-5-methylbenzaldehyde 
• 103260-54-4 1-(2-bromo-5-methyl-phenyl)-ethanol 

Downstream Products

• 1370529-64-8 C₁₇H₁₆O 
• 1383476-28-5 C₁₇H₁₆O₂ 
• 1370529-29-5 C₁₇H₁₆O₂ 
• 1370529-53-5 C₁₇H₁₈O 
• 1313762-41-2 4-methyl-2-vinylbenzaldehyde 

Relevant academic research and scientific papers

Palladium-Catalyzed Ring-Forming Aminoalkenylation of Alkenes with Aldehydes Initiated by Intramolecular Aminopalladation

A palladium-catalyzed aminopalladation reaction followed by nucleophilic addition with aldehydes and dehydration is described. This direct and operationally simple procedure provides a rapid and reliable approach to a wide range of functionalized tetrahydroisoquinolines with high selectivity. Mechanistic studies disclosed that the nucleophilic addition, performed via a highly ordered transition-state, is the turnover-limiting step in which the inherent β-hydride elimination of the key Csp3?Pd species was controlled by the confined conformation and the nucleophilicity of the Csp3?Pd bond was enhanced by the strong electron-donating effect of the nitrogen atom.

Photochemical studies on aromatic γ,δ-epoxy ketones: Efficient synthesis of benzocyclobutanones and indanones

Irradiation of terminal aromatic γ,δ-epoxy ketones with a 450 W UV lamp led to Norrish type II cyclization/semi-pinacol rearrangement cascade reaction which formed the benzocyclobutanones containing a full-carbon quaternary center, whereas irradiation of substituted aromatic γ,δ-epoxy ketones led to the indanones through a photochemical epoxy rearrangement and 1,5-biradicals cyclization tandem reaction.