90560-54-6

Basic information

• Product Name: N-(2-BROMO-4-METHYL-PHENYL)-2-CHLORO-ACETAMIDE
• Synonyms: N-(2-bromo-4-methyl-phenyl)-2-chloro-ethanamide
• CAS NO: 90560-54-6
• Molecular Formula: C₉H₉BrClNO
• Molecular Weight: 262.54
• Mol File: 90560-54-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 382.2°Cat760mmHg
• Flash Point: 184.9°C
• Appearance: /
• Density: 1.578g/cm³
• Vapor Pressure: 4.82E-06mmHg at 25°C
• Refractive Index: 1.612
• CAS DataBase Reference: N-(2-BROMO-4-METHYL-PHENYL)-2-CHLORO-ACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-BROMO-4-METHYL-PHENYL)-2-CHLORO-ACETAMIDE(90560-54-6)
• EPA Substance Registry System: N-(2-BROMO-4-METHYL-PHENYL)-2-CHLORO-ACETAMIDE(90560-54-6)

Safety Data

• Hazardous Substances Data: 90560-54-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H9BrClNO/c1-6-2-3-8(7(10)4-6)12-9(13)5-11/h2-4H,5H2,1H3,(H,12,13)

Upstream product

• 583-68-6 2-bromo-p-toluidine 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 96079-26-4 N,N-diethyl-glycine-(2-bromo-4-methyl-anilide); hydrochloride 
• 1198271-67-8 N-(2-bromo-4-methylphenyl)-2-(4-(naphthalen-2-yl)-1,2,3-thiadiazol-5-ylthio)acetamide 
• 1492902-42-7 N-(2-bromo-4-methylphenyl)-2-(4-(4-tert-butylphenyl)-5-isopropyl-4H-1,2,4-triazol-3-ylthio)acetamide 
• 1352228-73-9 C₂₃H₁₈BrN₃OS 
• 1352228-88-6 C₁₉H₁₅BrClN₃OS 
• 1383786-79-5 C₂₄H₂₃BrN₄OS 
• 1200397-79-0 N-(2-bromo-4-methylphenyl)-2-{[4-(3,4-dichlorophenyl)-1,2,3-thiadiazol-5-yl]sulfanyl}acetamide 
• 1190213-47-8 N-(2-bromo-4-methylphenyl)-2-(4-(3,4-dichlorophenyl)-1,2,3-selenadiazol-5-ylthio)acetamide 
• 1126472-47-6 N-(2-bromo-4-methylphenyl)-2-(1-(4-chlorophenyl)-1H-imidazol-2-ylthio)acetamide 
• 1187945-87-4 N-(2-bromo-4-methylphenyl)-2-(1-(naphthalen-1-yl)-1H-imidazol-2-ylthio)acetamide 
• 1187945-92-1 N-(2-bromo-4-methylphenyl)-2-(1-p-tolyl-1H-imidazol-2-ylthio)acetamide 

Relevant articles and documents

New 4,5-diphenylimidazole-acetamide-1,2,3-triazole hybrids as potent α-glucosidase inhibitors: synthesis, in vitro and in silico enzymatic and toxicity evaluations

Herein, a new series of 4,5-diphenylimidazole-acetamide-1,2,3-triazole hybrids as potent α-glucosidase inhibitors was designed and synthesized. All the synthesized compounds exhibited excellent inhibition potencies (IC50 values = 55.6–149.2 μM)

Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase

A new series of 1,2,4-triazoles was synthesized and tested against several NNRTI-resistant HIV-1 isolates. Several of these compounds exhibited potent antiviral activities against efavirenz- and nevirapine-resistant viruses, containing K103N and/or Y181C mutations or Y188L mutation. Triazoles were first synthesized from commercially available substituted phenylthiosemicarbazides, then from isothiocyanates, and later by condensing the desired substituted anilines with thiosemicarbazones.