905836-52-4

Upstream product

• 193338-94-2 (5S,1'S)-carbetoxy-5-<1-<<(1',1-dimethylothoxy)carbonyl>amino>-2-phenylmethyl>dihydrofuran-2(3H)-one 
• 52199-24-3 2-[(4-bromomethyl)phenyl]pyridine 
• 105-53-3 diethyl malonate 
• 98760-08-8 (2R,3S)-3-[N-(tert-butyloxycarbonyl)amino]-1,2-epoxy-4-phenylbutane 

Downstream Products

• 905836-53-5 tert-butyl (1S)-1-((2S,4S)-5-oxo-4-(4-(pyridin-2-yl)benzyl)tetrahydrofuran-2-yl)-2-phenylethylcarbamate 
• 905836-58-0 [(1S,2S,4S)-1-benzyl-4-carbamoyl-2-hydroxy-5-(4-pyridin-2-ylphenyl)pentyl]carbamic acid tert-butyl ester 
• 1053713-87-3 [(1S,2S,4S)-4-Amino-1-benzyl-5-(4-pyridin-2-yl-phenyl)-2-triethylsilanyloxy-pentyl]-carbamic acid tert-butyl ester 
• 905836-59-1 [(1S,2S,4S)-1-benzyl-4-carbamoyl-5-(4-pyridin-2-ylphenyl)-2-triethylsilanyloxypentyl]carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

An efficient, stereoselective synthesis of the hydroxyethylene dipeptide isostere core for the HIV protease inhibitor A-792611

A stereoselective synthesis of the hydroxyethylene dipeptide isostere 1 is described. The route employs a substrate-directed kinetic protonation of an α/γ-substituted lactone to afford the desired stereochemistry. A method for converting the diastereomeri