906065-60-9

Upstream product

• 3972-64-3 1-bromo-3-(tertbutyl)benzene 
• 3125-64-2 3-methoxyphenyl isothiocyanate 
• 103273-01-4 2-bromo-4-tert-butylaniline 
• 769-92-6 4-tert-Butylaniline 

Downstream Products

• 929042-18-2 5-(3-tert-butylphenyl)-4-(3-methoxyphenyl)-N,N-dimethyl-4H-1,2,4-triazol-3-amine 
• 581814-67-7 1-{3-[3-(tert-butyl) phenyl]-(1,2,4-triazol-4-yl)}-3-methoxybenzene 

Relevant academic research and scientific papers

Efficient new approach for the synthesis of N,N-dialkylamino-1,2,4-triazoles

A series of 3-NN-dialkylamino-4,5-diaryl-1,2,4-triazoles were synthesized in high yield under mild reaction conditions by coupling functionalized arylmagnesiums with isothiocyanates and cyclization with Viehe's salts. No selective thionation reaction was

Discovery of novel triazole-based opioid receptor antagonists

We report the computer-aided design, chemical synthesis, and biological evaluation of a novel family of δ opioid receptor (DOR) antagonists containing a 1,2,4-triazole core structure that are structurally distinct from other known opioid receptor active l