90609-47-5

Basic information

• Product Name: 1-IODO-2,6-DIMETHYL-4-METHOXYBENZENE
• Synonyms: 1-IODO-2,6-DIMETHYL-4-METHOXYBENZENE;4-IODO-3,5-DIMETHYLANISOLE
• CAS NO: 90609-47-5
• Molecular Formula: C₉H₁₁IO
• Molecular Weight: 262.09
• Mol File: 90609-47-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-IODO-2,6-DIMETHYL-4-METHOXYBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-IODO-2,6-DIMETHYL-4-METHOXYBENZENE(90609-47-5)
• EPA Substance Registry System: 1-IODO-2,6-DIMETHYL-4-METHOXYBENZENE(90609-47-5)

Safety Data

• Hazardous Substances Data: 90609-47-5(Hazardous Substances Data)

Usage

Structure

A derivative of benzene with a methyl group and a methoxy group in the ortho position, and an iodine atom in the para position.

Usage

As a precursor in organic synthesis, in the production of pharmaceuticals and agrochemicals, and as an intermediate in the manufacture of dyes, pigments, and fragrances.

Reactivity

Can undergo various types of organic reactions, including nucleophilic substitution and metal-catalyzed cross-coupling reactions, making it a versatile building block in organic chemistry.

Handling

Should be handled with caution and in controlled environments due to its potentially hazardous nature.

Upstream product

• 6267-34-1 2-bromo-5-methoxy-1,3-dimethyl-benzene 
• 108-68-9 3,5-Dimethylphenol 
• 80826-86-4 4-iodo-3,5-dimethylphenol 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 874-63-5 3,5-dimethylmethoxybenzene 
• 19447-00-8 4-methoxy-2,6-dimethylbenzylaldehyde 
• 1202711-17-8 [(C₅H₅)Fe(C₅H₄B(C₆H₂(CH₃)2OCH₃)2)] 
• 74331-73-0 (2,6-Dimethyl-4-methoxyphenyl)acetylene 

Relevant articles and documents

Chiral probe development for circularly polarised luminescence: Comparative study of structural factors determining the degree of induced CPL with four heptacoordinate europium(III) complexes

A series of bright, europium(iii) complexes has been prepared based on an achiral heptadentate triazacyclononane ligand bearing two strongly absorbing, coordinated aralkynyl pyridyl moieties. The binding of chiral carboxylates, including α-hydroxy acids such as lactate and mandelate, has been monitored by emission spectroscopy and is signalled by the switching on of strong circularly polarised emission. In each case, an R-chiral carboxylate gave rise to emission typical of a Δ complex, most clearly shown in the form of the ΔJ = 4 transition manifold around 700 nm. Variations in the sign and magnitude of the CPL allow the enantiomeric purity and absolute configuration of the acid to be assessed in a sample. Analysis of the relative energies of the parent aqua complexes and their stereoisomeric adducts has been aided by lifetime measurements and density functional theory calculations.

Linear bilateral extended 2,2′:6′,2′′-terpyridine ligands, their coordination complexes and heterometallic supramolecular networks

Octahedral metal complexes of tridentate 2,2′:6′,2′′-terpyridine (terpy) fused with five-membered furan rings mimic the topology of tetrahedral metal complexes of bidentate 5,5′-functionalized 2,2′-bipyridine (bipy). Herein, we report the robust synthesis of 2,6-bis(2-substituted-furo[2,3-c]pyridine-5-yl)pyridine based ligands to access a series of linear bilateral extended terpy derivatives. This molecular design of alternating five- and six-membered rings has been applied to extend the applicability of terpy as a building block in supramolecular chemistry. The complexation of 2,6-bis(2-substituted-furo[2,3-c]pyridine-5-yl)pyridine derivatives with metal ions preferring octahedral geometry (Fe2+, Ru2+, and Zn2+) gives molecular "crossings" and "corners". Such design elements, functionalized with 4-pyridyl groups, allowed the construction of 3D and 2D heterometallic supramolecular networks containing Fe2+, Ag+or Fe2+, Cu+metal centers.

Modified o-methyl-substituted IBX: room temperature oxidation of alcohols and sulfides in common organic solvents

o-Methyl-substituted Me-IBX is the first modified analog of IBX that oxidizes alcohols in common organic solvents at room temperature, due to a composite of two factors, that is, low solubility and hypervalent twisting-promoted rate enhancement. Furthermore, the reagent is efficient for selective oxidation of sulfides to sulfoxides, a transformation that otherwise occurs only sluggishly with standard IBX. The facile synthetic accessibility and its mild as well as non-hazardous nature render Me-IBX a stable equivalent of Dess-Martin periodinane reagent in organic oxidations.