9063-57-4

Usage

Uses

Used in Immunotherapy:
Tuftsin is used as an immunomodulatory agent for enhancing the immune response against various diseases. Its ability to stimulate the activity of immune cells and promote antibody production makes it a promising candidate for the treatment of cancer, autoimmune disorders, and infectious diseases.
Used in Cancer Treatment:
In the field of oncology, tuftsin is used as a therapeutic agent for its potential to boost the immune system's ability to recognize and eliminate cancer cells. It has been investigated for its synergistic effects when combined with conventional cancer therapies, potentially improving treatment outcomes and patient prognosis.
Used in Vaccine Development:
Tuftsin is utilized as an adjuvant in vaccine development to enhance the body's immune response to vaccines. Its immunostimulatory properties can potentially improve the efficacy of vaccines, leading to better protection against various infectious diseases.
Used in Autoimmune Disease Management:
In the context of autoimmune disorders, tuftsin is employed as a therapeutic agent to modulate the immune system's response. Its ability to regulate immune cell activity may help in managing the symptoms and progression of autoimmune diseases by reducing inflammation and tissue damage.
Overall, tuftsin's diverse applications across various industries, including healthcare, pharmaceuticals, and biotechnology, highlight its potential as a valuable tool in the fight against numerous health challenges.

InChI:InChI=1/C21H40N8O6/c1-12(30)16(23)18(32)27-13(6-2-3-9-22)19(33)29-11-5-8-15(29)17(31)28-14(20(34)35)7-4-10-26-21(24)25/h12-16,30H,2-11,22-23H2,1H3,(H,27,32)(H,28,31)(H,34,35)(H4,24,25,26)

Upstream product

• 154508-97-1 Boc-Lys(2Cl,Z)-Pro-Arg(Tos)-OBn 
• 3304-59-4 N-benzyloxycarbonyl-L-proline p-nitrophenyl ester 
• 55322-38-8 (α-Benzyloxycarbonyl-ε-tert-butoxycarbonyllysyl)prolylarginine 
• 60889-67-0 N-benzyloxycarbonyl-L-prolyl-L-arginine 
• 2212-69-3 N₂-benzyloxycarbonyl-N₆-t-butoxycarbonyl-L-lysine 4-nitrophenyl ester 
• 74-79-3 L-arginine 
• 66336-81-0 Boc-Pro-Arg(Tos)-OBn 
• 66336-82-1 H-Pro-Arg(Tos)-OBn 
• 61543-20-2 Boc-Arg(Tos)-OBzl 
• 13836-37-8 Boc-Arg(Tos)-OH 
• 29388-63-4 H-Arg(Tos)-OBzl 
• 154509-00-9 Boc-Thr(OBn)-Lys(2Cl,Z)-Pro-Arg(Tos)-OBn 
• 78432-02-7 Benzyloxycarbonylthreonyl(ε-tert-butoxycarbonyllysyl)prolylarginine 

Downstream Products

• 72-19-5 L-threonine 
• 56-87-1 L-lysine 
• 74-79-3 L-arginine 
• 147-85-3 L-proline 

Relevant academic research and scientific papers

Enantiospecific C-H Activation Using Ruthenium Nanocatalysts

The activation of C-H bonds has revolutionized modern synthetic chemistry. However, no general strategy for enantiospecific C-H activation has been developed to date. We herein report an enantiospecific C-H activation reaction followed by deuterium incorporation at stereogenic centers. Mechanistic studies suggest that the selectivity for the α-position of the directing heteroatom results from a four-membered dimetallacycle as the key intermediate. This work paves the way to novel molecular chemistry on nanoparticles.

Thioacylating Agents. Use of Thiobenzimidazolone Derivatives for the Preparation of Thiotuftsin Analogs.

The properties and characteristic reactions of thioacylating reagents 1 are described.These reagents are able to introduce thioamide linkages into a growing peptide at a specific site in the sequence.The generality and efficiency of this methodology is demonstrated by the synthesis of the three monothioanalogues of tuftsin.

Method for protecting guanidino group and restoring the same

A guanidino group in an amino acid or a peptide can be protected with a specific protective group, i.e. lower alkoxybenzenesulfonyl group or tri-lower alkylbenzenesulfonyl group, and the protective group may easily be removed without affecting the amino acid or the peptide to be derived from the protected amino acid or peptide. Thus, the method is useful in the related chemical industries, especially in the peptide synthesis.