90678-72-1

Upstream product

• 68892-42-2 N-isobutyryl-2'-deoxyguanosine 
• 100-27-6 2-(4-nitrophenyl)ethanol 
• 93130-37-1 Acetic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{2-isobutyrylamino-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-tetrahydro-furan-3-yl ester 
• 86702-72-9 4-Oxo-pentanoic acid (2R,3S,5R)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-5-{2-isobutyrylamino-6-[2-(4-nitro-phenyl)-ethoxy]-purin-9-yl}-tetrahydro-furan-3-yl ester 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 82921-57-1 N²-isobutyryl-O⁶-<2-(p-nitrophenyl)ethyl>-2'-deoxyguanosine 

Downstream Products

• 102691-37-2 2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-N²-isobutyryl-O⁶-[2-(4-nitrophenyl)ethyl]guanosine 3'-(2-cyanoethyl diisopropylphosphoramidite) 
• 93183-95-0 5'-O-dimethoxytrityl-N²-isobutyryl-O⁶-<2-(p-nitrophenyl)ethyl>-2'-deoxyguanosine 3'-(2-chlorophenyl,2-cyanoethyl)phosphate 

Relevant academic research and scientific papers

Improved Synthesis of Oligodeoxyribonucleotides by Solid-Phase Phosphotriester Method Utilizing O6--2'-deoxyguanosine Derivatives

The synthesis of oligodeoxyribonucleotides on a cross-linked polystyrene solid support utilizing stable mono- and dinucleotide phosphotriester building blocks is presented.The use of O6--2'deoxyguanosine derivatives yields cleaner DNA fragments by supressing side reactions.Modifications improving the phosphotriester methodology are presented.The purification methods and analysis of synthetic oligodeoxyribonucleotides are described.

THE INFLUENCE OF THE PURINE 2-AMINO GROUP ON DNA CONFORMATION AND STABILITY - II SYNTHESIS AND PHYSICAL CHARACTERIZATION OF d, d, AND d

Synthesis of an N-protected derivative of 2-amino-2'-deoxyadenosine (dA') from 2'-deoxyguanosine is reported.The syntheses of several oligodeoxynucleotides containing this modified nucleoside are described, together with physical characterization via melt