102691-37-2 Usage
Uses
Used in Medicinal Chemistry:
(2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE is used as a key intermediate in the synthesis of nucleoside analogs for its ability to introduce specific functional groups and structural elements into target molecules.
Used in Drug Development:
In the pharmaceutical industry, (2R,3S,5R)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-5-(2-ISOBUTYRAMIDO-6-(4-NITROPHENETHOXY)-9H-PURIN-9-YL)TETRAHYDROFURAN-3-YL 2-CYANOETHYL DIISOPROPYLPHOSPHORAMIDITE serves as a crucial building block for the development of new drugs, particularly those targeting various diseases and conditions. Its unique structure allows for the creation of bioactive molecules with potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 102691-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,6,9 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 102691-37:
(8*1)+(7*0)+(6*2)+(5*6)+(4*9)+(3*1)+(2*3)+(1*7)=102
102 % 10 = 2
So 102691-37-2 is a valid CAS Registry Number.
102691-37-2Relevant academic research and scientific papers
New 2-(4-nitrophenyl)ethyl(Npe)- and 2-(4- nitrophenyl)ethoxycarbonyl(Npeoc)protected 2'-deoxyribonucleosides and their 3'-phosphoramidites - Versatile building blocks for oligonucleotide synthesis
Lang, Holger,Gottlieb, Margarete,Schwarz, Michael,Farkas, Silke,Schulz, Bernd S.,Himmelsbach, Frank,Charubala, Ramamurthy,Pfleiderer, Wolfgang
, p. 2172 - 2185 (2007/10/03)
A series of new base-protected and 5'-O-(4-monomethoxytrityl)- or 5'-O- (4,4'-dimethoxytrityl)-substituted 3'-(2-cyanoethyl diisopropylphosphoramidites) and 3'-[2-(4-nitrophenyl)ethyl diisopropylphosphoramidites] 52-66 and 67-82, respectively, are prepare
POLYMER-SUPPORTED SYNTHESIS OF DEOXYOLIGONUCLEOTIDES USING IN SITU PREPARED DEOXYNUCLEOSIDE 2-CYANOETHYL PHOSPHORAMIDITES
Nielsen, J.,Marugg, J. E.,Taagaard, M.,Boom, J. H. van,Dahl, O.
, p. 33 - 34 (2007/10/02)
The easily acessibile reagent 2-cyanoethyl-bis(diisopropylamino)phosphoramidite is shown to be suitable for the in-situ, 1H-tetrazole catalysed, preparation of d-nucleoside-3'-phosphoramidites.THe latter compounds could be applied successfuly as building blocks in a solid-phase DNA synthesis using an automated DNA synthesizer.
