90708-66-0

Upstream product

• 539-12-8 4-Propenyl-phenol 
• 201230-82-2 carbon monoxide 
• 2628-17-3 4-Vinylphenol 
• 10210-17-0 3-(4-hydroxyphenyl)propan-1-ol 
• 540-38-5 p-Iodophenol 
• 107-18-6 allyl alcohol 

Relevant academic research and scientific papers

Synthesis of rac-ɑ-aryl propionaldehydes via branched-selective hydroformylation of terminal arylalkenes using water-soluble Rh-PNP catalyst

This work detailed the preparation of a class of water-soluble PNP ligands that differed by the nature of the substitute on phenyl ring of ligands. These ligands were incorporated into water-soluble rhodium-PNP complex catalysts that were used to regioselective hydroformylation of a series of terminal arylalkenes, providing efficient access to rac-α-aryl propionaldehydes in good to excellent yield (up to 97%) and branched-regioselectivity (up to 40:1 b/l ratio). Furthermore, gram-scale and diverse synthetic transformation demonstrated synthetic application of this methodology for non-steroidal antiinflammatory drugs.

Heck arylation of allyl alcohol catalyzed by Pd(0) nanoparticles

Pd(0) nanoparticles ca. 2 nm in diameter were obtained by the reduction of PdCl2 and Pd(OAc)2 in water at 80 °C in the presence of a PVP-stabilizing polymer. Pd(0) NPs were successfully used in the Heck coupling of allyl alcohol with iodo- and bromobenzenes. Iodobenzenes reacted under solventless conditions or in DMF solution producing 3-arylpropanals and 2-arylpropanals as the main products. The same products were obtained in the reaction of bromobenzene in TBAB as the reaction medium. The stability of Pd(0) NPs was evidenced in recycling experiments. Similar Heck coupling results were also obtained with the palladium compounds PdCl2(cod) and Pd(OAc)2 under the same conditions.

Polyalkylene Polymer Compounds and Uses Thereof

The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as c

Polyalkylene polymer compounds and uses thereof

The invention relates to novel polyalkylene glycol compounds and methods of using them. In particular, compounds comprising a novel polyethylene glycol conjugate are used alone, or in combination with antiviral agents to treat a viral infection, such as c

Hydroformylation of monosubstituted alkenes catalyzed by W-Rh bimetallic complex

By using a heterobimetallic catalyst, (CO)4(PEtPh 2)-W(μ-PPh2)Rh(CO)(PPh3), chemoselective hydroformylation of monosubstituted alkenes proceeds efficiently at room temperature under atmospheric pressure of CO/H

Solid-Liquid Biphasic Hydroformylation of Olefins Catalyzed by Rhodium Carhonyl Complexes

Some polymer-anchored alkenes have been hydroformylated by carrying out the reaction in a high-pressure reactor equipped with a suitably designed vial. The solid substrates are converted to the corresponding oxo-aldehydes in high yields. In all cases the regioselectivity was strongly shifted towards the linear aldehyde when the rhodium carbonyl complex was modified with xantphos (3:1 or 4:1 P/Rh molar ratio). Treatment with 5% of trifluoroacetine acid in dichloromethane at room temperature removed quantitatively the oxo-product from the polymer support, which can be purified and reused.

A FACILE PREPARATION OF 2-ARYLPROPIONALDEHYDE FROM 1-ARYL-1-PROPENE

1-Aryl-1-propenes were converted into the corresponding 2-arylpropionaldehydes in high yields by treatment with iodine and silver(I)oxide in aqeous dioxane at room temperature.