90736-63-3Relevant academic research and scientific papers
A convenient synthesis of Δ7,8-Morphinan-6-one and its direct oxidation to 14-hydroxy-Δ7,8-morphinan-6-one
Passarella, Daniele,Consonni, Alessandra,Giardini, Alessandra,Lesma, Giordano,Silvani, Alessandra
, p. 1981 - 1983 (2007/10/03)
Synthesis of Δ7,8-morphinan-6-one by Grewe cyclization and bromoketalization reaction as crucial steps is described. Introduction of a hydroxyl group at 14-position is demonstrated by direct oxidation with MnO2 in the presence of silica gel.
Oxidation of 1-Benzyl-3,4-dihydroisoquinolines Using Active Manganese Dioxide
Amaravathi, M.,Kumari, L. Krishna,Pardhasaradhi, M.
, p. 1246 - 1247 (2007/10/02)
Oxidation of 1-benzyl-3,4-dihydroisoquinolines (I, IV-VII) by active MnO2 affords the corresponding 1-benzoyl-3,4-dihydroisoquinolines in yields >80percent, except in the case of VI which gives the oxidation product in 46percent yield.
