90760-99-9

Upstream product

• 93-56-1 phenylethane 1,2-diol 
• 96-09-3 styrene oxide 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 
• 17199-29-0 (S)-Mandelic acid 

Downstream Products

• 73627-97-1 3-hydroxy-3-phenylpropanenitrile 
• 124718-93-0 2-azido-2-phenylethanol 
• 1004-99-5 2-chloro-2-phenylethanol 
• 1674-30-2 1-phenyl-2-chloroethanol 
• 34971-29-4 methyl tetrahydro-2-oxo-4-phenyl-3-furancarboxylate 
• 122-78-1 phenylacetaldehyde 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 108-88-3 toluene 
• 2979-22-8 2-methoxy-2-phenylethanol 

Relevant academic research and scientific papers

Preparation method and application of cyclic sulfate compound

The invention belongs to the technical field of organic synthesis, and particularly relates to a preparation method and application of a cyclic sulfate compound. One embodiment of the invention provides a preparation method of a cyclic sulfate compound. The cyclic sulfate compound is prepared from a compound A and sulfur-containing oxide, wherein the structural formula of the compound A is shown in the specification, R is selected from one of H, alkyl, alkenyl, substituted alkyl, aryl and halogen, X is C or S, and Y is-CH2-CH2-or-CH = C-. The compound A and sulfur trioxide are reliable in source, low in price, mild in reaction condition, easy to operate, free of waste water in the reaction process, few in three wastes, good in product quality, suitable for large-scale production, capable of obtaining the high-purity battery-grade ethylene sulfate compound, and relatively high in implementation value and social and economic benefits.

Synthesis of Cyclic Sulfite Diesters and their Evaluation as Sulfur Dioxide (SO2) Donors

Although sulfur dioxide (SO2) finds widespread use in the food industry as its hydrated sulfite form, a number of aspects of SO2 biology remain to be completely understood. Of the tools available for intracellular enhancement of SO2 levels, most suffer from poor cell permeability and a lack of control over SO2 release. We report 1,2-cyclic sulfite diesters as a new class of reliable SO2 donors that dissociate in buffer through nucleophilic displacement to produce SO2 with tunable release profiles. We provide data in support of the suitability of these SO2 donors to enhance intracellular SO2 levels more efficiently than sodium bisulfite, the most commonly used SO2 donor for cellular studies.

A Copper Metal–Organic Hydrogel as a Catalyst for SO2 and CO2 Fixation under Ambient Conditions

A copper metal–organic hydrogel (MOG) has been synthesized using an amino acid-based ligand, Na2HL {H3L = 2-{(3,5-di-tert-butyl-2-hydroxybenzyl)amino succinic acid} as a gelator. The metallohydrogel exhibits pH-responsive nature as well as chemical responsiveness. Besides, it shows rapid thixotropic behavior when external mechanical forces are applied. The metal–organic hydrogel can be used as a heterogeneous catalyst for the reaction of SO2 and CO2 with epoxides to produce cyclic 1,3,2-dioxathiolane-2-oxides and carbonates, respectively. The conversions were found to be dependent on the size and type of the side chain of the epoxides.

Ionic Pathways in the Photochemistry of Cyclic Sulfite Esters

The photochemistry of cyclic carbonate esters proceeds by the photochemical extrusion of carbon dioxide to give 1, 3-diradicals which produce oxiranes as well as other radical derived species. The corresponding cyclic sulfite esters, upon irradiation, give intermediates that are trapped by alcohols yet generate no oxiranes. These results are consistent with ionic intermediates.

Aluminum-Catalyzed Formation of Functional 1,3,2-Dioxathiolane 2-Oxides from Sulfur Dioxide: An Easy Entry towards N-Substituted Aziridines

Aluminum(III) complexes derived from aminotriphenolate ligands are shown to be excellent catalysts for the formation of cyclic sulfites from a range of (functionalized) terminal and internal epoxides, and ex situ generated sulfur dioxide. The developed catalytic protocol is characterized by its operational simplicity, wide scope in epoxide reaction partners, good to excellent isolated yields and mild reaction conditions [50–70 °C, p(SO2) a three-step protocol. (Figure presented.).

Photoreactions of cyclic sulfite esters: Evidence for diradical intermediates

The photochemistry of a phenyl and 1, 2-diphenyl substituted sulfite ester is reported. The performance of photoreactions under relatively mild reaction conditions enables the detection of products that have not been observed in previous studies. It is concluded that, complementary to the initially proposed carbene intermediates, diradicals may also be considered.

Preparation of cyclic sulfites by transesterification of diols and diisopropyl sulfite

Cyclic sulfites of 1,2-, 1,3- and 1,4-diols can be prepared in high yield by acid or base catalyzed transesterification with diisopropyl sulfite.

THE STEREOCHEMICAL COURSE OF SULPHURYL TRANSFER REACTIONS

A general strategy has been developed for the synthesis of chiral sulphate monoesters of known absolute configuration and a method for determining the absolute configuration of chiral sulphate monoesters by FT infrared spectros

The Crystal Structure of Some 2-Oxo-1,3,2-dioxathiolanes

The trans diastereoisomers of 2-oxo-4(S)-phenyl-1,3,2-dioxathiolane and meso-2-oxo-4,5-diphenyl-1,3,2-dioxathiolane have been unambiguously identified by X-ray analysis; both adopt the half-chair conformation and differential endocyclic S-O bond lengths provide evidence for a stereoelectronic interaction with the S=O group.