90763-47-6

Upstream product

• 68255-77-6 2-methoxy-4-chloro-5-nitrobenzoic acid 

Downstream Products

• 68255-78-7 N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-methoxy-4-chloro-5-nitrobenzamide 
• 179535-18-3 5-amino-N-(1-ethyl-1H-hexahydroazepin-3-yl)-2-methoxy-4-methylaminobenzamide 
• 204759-11-5 5-Amino-4-ethylamino-N-(1-ethyl-azepan-3-yl)-2-methoxy-benzamide 
• 179535-17-2 N-(1-ethyl-1H-hexahydroazepin-3-yl)-2-methoxy-4-methylamino-5-nitrobenzamide 
• 213627-51-1 4-Ethylamino-N-(1-ethyl-azepan-3-yl)-2-methoxy-5-nitro-benzamide 
• 213627-52-2 N-(1-Ethyl-azepan-3-yl)-2-methoxy-5-nitro-4-propylamino-benzamide 
• 213627-53-3 N-(1-Ethyl-azepan-3-yl)-4-isopropylamino-2-methoxy-5-nitro-benzamide 
• 90763-42-1 C₂₀H₃₃ClN₄O₄S 
• 90763-45-4 C₁₆H₂₅ClN₄O₄S 
• 90763-36-3 4-Chloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-(2,2,2-trifluoro-acetylamino)-benzamide 
• 90763-32-9 N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-methoxy-4-chloro-5-<(methylsulfamoyl)amino>benzamide 
• 90763-39-6 4-Chloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-methoxy-5-methylamino-benzamide 
• 68256-41-7 N-<(1-ethyl-2-pyrrolidinyl)methyl>-2-methoxy-4-chloro-5-methanesulfonamidobenzamide 
• 68256-23-5 N-(1-ethyl-2-pyrrolidinylmethyl)-2-methoxy-4-chloro-5-t-butylaminosulfonamidobenzamide 

Relevant academic research and scientific papers

A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with dual antiemetic and gastroprokinetic activities

A novel series of 6-methoxy-1H-benzotriazole-5-carboxamide derivatives with a medium perhydroazacycle ring in the amine moiety were prepared, and their antiemetic and gastroprokinetic activities were evaluated. Among them, N-(1-ethylhexahydroazepin-3-yl)-, N-(1-ethyloctahydroazocin-3-yl)- and N-(1- ethyloctahydroazonin-3-yl)-6-methoxy-1H-benzotriazole-5-carboxamides (24, 36, 37) showed a potent antiemetic activity (inhibition of apomorphine-induced emesis in dogs) along with gastroprokinetic activity (gastric emptying in rats).

Synthesis and Neuroleptic Activity of N--2-methoxy-5-sulfonamidobenzamides

A series of some novel N-benzamides involving replacement of the sulfamoyl group in sulpiride with a sulfonamido group was synthesized and tested for dopamine receptor blockade.In comparison with sulpiride, several compounds were considerably more potent than sulpiride as dopamine receptor blockers.The structure-activity relationships are discussed.