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Usage

Uses

Used in Pharmaceutical Industry:
2-Methoxy-4-methyl-5-pyrimidinamine is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to contribute to the development of new drugs with potential therapeutic effects. Its unique structure allows for the creation of molecules that can target specific biological pathways, making it valuable in the discovery and production of medications for treating a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Methoxy-4-methyl-5-pyrimidinamine is utilized as an intermediate in the production of pesticides and other crop protection agents. Its incorporation into these chemicals can enhance their effectiveness in controlling pests and diseases, thereby contributing to increased crop yields and improved agricultural productivity.
Given the compound's role in biological processes and its potential applications across different industries, ongoing research and development efforts are focused on exploring and expanding its use in creating innovative solutions for healthcare and agriculture.

Upstream product

• 20090-69-1 2-chloro-4-methyl-5-aminopyrimidine 
• 124-41-4 sodium methylate 
• 84538-47-6 4-chloro-2-methoxy-6-methyl-5-nitropyrimidine 

Relevant academic research and scientific papers

Preparation method of 2-methoxy-5-amino-4-methylpyrimidine

The invention discloses a preparation method of 2-methoxy-5-amino-4-methylpyrimidine, and belongs to the technical field of organic chemistry. The method comprises the following steps: carrying out ahydrogenation reaction by taking 2-methoxy-5-nitro-4-methyl-6-chloropyrimidine as a raw material, methanol as a solvent, triethylamine as an acid-binding agent and nickel as a catalyst to generate a mixture of 2-methoxy-5-amino-4-methylpyrimidine and other impurities, filtering, extracting, drying, and freezing to obtain a pure product 2-methoxy-5-amino-4-methylpyrimidine with the yield of 71-86%.According to the preparation method, the defects of the existing synthesis process are overcome, and a new method for synthesizing 2-methoxy-5-amino-4-methylpyrimidine is provided.

Therapeutically Active Thiazolo-Pyrimidine Derivatives

A series of thiazolo[5,4-d]pyrimidine derivatives of formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: (I) Q represents a group of formula (Qa), (Qb), (Qc), (Qd) or (Qe) are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection.

THERAPEUTICALLY ACTIVE THIAZOLO-PYRIMIDINE DERIVATIVES

A series of thiazolo[5,4-d]pyrimidine derivatives of formula (I) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: (I) Q represents a group of formula (Qa), (Qb), (Qc), (Qd) or (Qe) are beneficial in the treatment and/or prevention of various human ailments, including inflammatory, autoimmune and oncological disorders; viral diseases; and organ and cell transplant rejection.