908373-11-5Relevant articles and documents
Artepillin C isoprenomics: Design and synthesis of artepillin C isoprene analogues as lipid peroxidation inhibitor having low mitochondrial toxicity
Uto, Yoshihiro,Ae, Shutaro,Koyama, Daisuke,Sakakibara, Mitsutoshi,Otomo, Naoki,Otsuki, Mamoru,Nagasawa, Hideko,Kirk, Kenneth L.,Hori, Hitoshi
, p. 5721 - 5728 (2007/10/03)
We designed and synthesized isoprene analogues of artepillin C, a major component of Brazilian propolis, and investigated the inhibitory activity on lipid peroxidation of rat liver mitochondria (RLM) and RLM toxicity based on isoprenomics. We succeeded in