151071-03-3

Basic information

• Product Name: 4-IODO-2-(3-METHYL-2-BUTENYL)-PHENOL
• Synonyms: 4-IODO-2-(3-METHYL-2-BUTENYL)-PHENOL
• CAS NO: 151071-03-3
• Molecular Formula: C₁₁H₁₃IO
• Molecular Weight: 288.12479
• Mol File: 151071-03-3.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-IODO-2-(3-METHYL-2-BUTENYL)-PHENOL(CAS DataBase Reference)
• NIST Chemistry Reference: 4-IODO-2-(3-METHYL-2-BUTENYL)-PHENOL(151071-03-3)
• EPA Substance Registry System: 4-IODO-2-(3-METHYL-2-BUTENYL)-PHENOL(151071-03-3)

Safety Data

• Hazardous Substances Data: 151071-03-3(Hazardous Substances Data)

Upstream product

• 540-38-5 p-Iodophenol 
• 870-63-3 prenyl bromide 

Downstream Products

• 1208233-15-1 tert-butyl (2E)-3-[3-(3-methylbut-2-en-1-yl)-4-[(3-phenylpropanoyl)oxy]phenyl]prop-2-enoate 
• 1303962-66-4 (E)-methyl 3-{3-(3-methylbut-2-en-1-yl)-4-[(2-methylbut-3-yn-2-yl)-oxy]phenyl}acrylate 
• 72704-01-9 (E)-methyl 3-[4-Hydroxy-3-(3-methylbut-2-en-1-yl)phenyl]acrylate 
• 1208233-13-9 4-iodo-2-(3-methylbut-2-en-1-yl)phenyl-3-phenylpropanoate 
• 1208233-14-0 tert-butyl (E)-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]acrylate 
• 1208233-19-5 1-(2-methylbut-3-yn-2-yloxy)-4-iodo-2-(3-methylbut-2-enyl)benzene 
• 151071-02-2 methyl (E)-3-[4-(acetyloxy)-3-(3-methyl-2-butenyl)phenyl]-2-propenoate 
• 53755-58-1 drupanin 
• 908373-11-5 methyl (E)-3-[4-(acetyloxy)-3-[(2E)-3,7-dimethyl-2,6-octadienyl]-5-(3-methyl-2-butenyl)phenyl]-2-propenoate 

Relevant articles and documents

Potent and Highly Selective Aldo-Keto Reductase 1C3 (AKR1C3) Inhibitors Act as Chemotherapeutic Potentiators in Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia

Aldo-keto reductase 1C3 (AKR1C3) catalyzes the synthesis of 9α,11β-prostaglandin (PG) F2α and PGF2α prostanoids that sustain the growth of myeloid precursors in the bone marrow. The enzyme is overexpressed in acute myeloid leukemia (

Ph3PAuNTf2 as a superior catalyst for the selective synthesis of 2H-chromenes: Application to the concise synthesis of benzopyran natural products

Ph3PAuNTf2 (≈1 mol-%) catalyzes the selective cycloisomerization of substituted aryl propargyl ethers into 2H-chromenes in excellent yields. Benzofuran byproducts are formed only in the case of electron-deficient arenes, in up to 7% relative yield. The Ph 3PAuNTf2-catalyzed cyclization of aryl propargyl ethers was applied as a key step to the concise synthesis of the naturally occurring benzopyrans seselin, xanthyletin, precocenes I and II, 8-(3′,3′- dimethylallyl)wenteria chromene, and 2,2-dimethyl-8-prenylchromene-6-propenoic acid. Ph3PAuNTf2 is a general, highly efficient, and product-selective catalyst for the clean synthesis of 2H-chromenes from the cycloisomerization of aryl propargyl ethers.The Ph3PAuNTf 2-catalyzed cyclization was applied as a key step in the synthesis of several benzopyran-bearing naturally occurring substances. Copyright

First total synthesis of artepillin C established by o,o′-diprenylation of p-halophenols in water

We have demonstrated that prenylation of phalophenols was dependent on the solvent effect and succeeded in o,o′-diprenylation of p-halophenols in water. Following the Mizoroki-Heck coupling of the diprenyl-piodophenol 3c with methyl acrylate and then hydr