90852-19-0

Upstream product

• 2037-48-1 2-deoxystreptamine 
• 119-04-0 neomycin B 
• 84107-26-6 2-deoxystreptamine dihydrobromide 
• 108-24-7 acetic anhydride 
• 90899-14-2 (1α,2β,3α,4β,6β)-4,6-Diazido-1,2,3-cyclohexantriol 

Downstream Products

• 236115-61-0 [(1S,2S,3R,4S,6R)-2-acetoxy-4,6-diazido-3-hydroxy-cyclohexyl] acetate 
• 864862-16-8 (1R,2R,3S,4R,6S)-1-O-(6'-azido-6'-deoxy-2',3',4'-tri-O-benzyl-α-L-glucopyranosyl)-4,6-diazido-cyclohexan-2,3-ol 
• 864862-15-7 (1R,2S,3S,4R,6S)-1-O-(6'-azido-6'-deoxy-2',3',4'-tri-O-benzyl-α-L-glucopyranosyl)-2,3-diacetoxy-4,6-diazido-cyclohexanol 

Relevant academic research and scientific papers

Synthesis of neamine-based pseudodisaccharides as potential vestibulotoxic agents to treat vertigo in Me?nie?re's disease

Ménière's disease (MD) is a progressive disease of the inner ear characterized by recurring attacks of disabling vertigo, hearing loss and tinnitus. Patients who do not respond to vestibular sedatives or steroids may require an intratympanic application o

An efficient and improved procedure for preparation of triflyl azide and application in catalytic diazotransfer reaction

An efficient and improved procedure for preparation of triflyl azide and application in catalytic diazotransfer reaction are described. The amount of highly toxic reagents NaN3 and Tf2O, is significantly reduced comparing with the pr

The chemistry of amine-azide interconversion: Catalytic diazotransfer and regioselective azide reduction

Azides have proven to be useful precursors to amines in organic syntheses. This report describes an improvement of the diazotransfer reaction and the first example of a regioselective azide reduction of compounds containing multiple azides. The use of a s

Design and synthesis of new aminoglycoside antibiotics containing neamine as an optimal core structure: Correlation of antibiotic activity with in vitro inhibition of translation

The structure and activity of the pseudodisaccharide core found in aminoglycoside antibiotics was probed with a series of synthetic analogues in which the position of amino groups was varied around the glucopyranose ring. The naturally occurring structure