90852-43-0

Basic information

• Product Name: 2-(benzylsulfanyl)-3-ethyl-4(3H)-quinazolinone
• Synonyms: 2-(benzylsulfanyl)-3-ethyl-4(3H)-quinazolinone
• CAS NO: 90852-43-0
• Molecular Formula: C₁₇H₁₆N₂OS
• Molecular Weight: 296.38674
• Mol File: 90852-43-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(benzylsulfanyl)-3-ethyl-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(benzylsulfanyl)-3-ethyl-4(3H)-quinazolinone(90852-43-0)
• EPA Substance Registry System: 2-(benzylsulfanyl)-3-ethyl-4(3H)-quinazolinone(90852-43-0)

Safety Data

• Hazardous Substances Data: 90852-43-0(Hazardous Substances Data)

Upstream product

• 21563-73-5 2-aminobenzoyl chloride 
• 6344-77-0 2-(benzylsulfanyl)quinazolin-4(3H)-one 
• 75-03-6 ethyl iodide 
• 118-92-3 anthranilic acid 
• 13906-09-7 2-thioxo-2,3-dihydro-1H-quinazolin-4-one 

Relevant articles and documents

Design, synthesis and biological activity evaluation of 2-mercapto-4(3H)-quinazolinone derivatives as novel inhibitors of protein tyrosine phosphatase 1B

A series of novel 2-mercapto-4(3H)-quinazolinone derivatives have been synthesized and their inhibitory effects on PTP1B and TCPTP are evaluated for the first time. Most of these derivatives showed good inhibitory activity on PTP1B and reasonable selectivity for PTP1B over TCPTP, among them 32 was the most potent PTP1B inhibitor (IC50 = 1.50 μ ;g/mL), and 27 possessed the best selectivity of 3.0-fold.