90862-01-4Relevant academic research and scientific papers
STUDIES OF PYRAZINES. PART 8. PYROLYSIS OF 2-ALKOXYPYRAZINES; SUBSTITUENT EFFECTS AND STEREOSPECIFICITY
Konakahara, Takeo,Sato, Kenji,Takagi, Yukio,Kuwata, Kazuhiko
, p. 641 - 646 (1984)
Twelve 2-alkoxypyrazines (R=iPr, sBu, 1,2-dimethylpropyl, 1,2,2-trimethylpropyl, t-butyl, t-pentyl, 1,1,2-trimethylpropyl, 1,1,2,2-tetramethylpropyl, octyl, neopentyl, +/--erythro- and +/--threo-2-deuterio-1,2-diphenylethyl) have been pyrolysed to elucidate the substituent effects on the rate and stereospecificity of the reaction.Activation parameters (log A and Ea) for the first eight compounds listed were determined.The reaction was accelerated by α-substitution; this was a combination of both polar and steric effects.The stereospecificity of the reaction was high.
