90874-41-2

Usage

Uses

Used in Organic Synthesis:
3-phenylcyclobutan-1-amine is used as a building block in organic synthesis for the production of various pharmaceuticals and agrochemicals. Its unique structure and reactivity allow for the creation of a wide range of compounds with potential applications in different industries.
Used in Medicinal Chemistry and Drug Discovery:
In the field of medicinal chemistry, 3-phenylcyclobutan-1-amine is utilized as a key intermediate in the synthesis of pharmaceuticals. Its unique structure and reactivity make it a valuable component in the development of new drugs with potential therapeutic benefits.
Used in Chemistry and Material Science:
3-phenylcyclobutan-1-amine may also have potential uses in the development of novel materials and functional molecules in the field of chemistry and material science. Its unique properties can contribute to the advancement of new materials with specific characteristics and applications.

Upstream product

• 99059-91-3 3-phenylcyclobutan-1-one oxime 
• 52784-31-3 3-Phenylcyclobutanone 
• 100-42-5 styrene 

Downstream Products

• 1401075-33-9 1-(1H-indazol-4-yl)-3-(cis-3-phenylcyclobutyl)urea 

Relevant academic research and scientific papers

Synthesis and in vitro evaluation of novel N-cycloalkylcarbamates as potential cholinesterase inhibitors

Abstract: This present paper describes the preparation and characterization of a series of O-substituted N-cycloalkylcarbamate derivatives. These compounds were tested as inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). All studied carbamates exhibited moderate inhibitory activity of both cholinesterases with values of IC50 in the range of 36.1–78.6?μM for AChE and 9.8–215.4?μM for BChE, respectively. These values are comparable with those values of inhibition obtained with the established drug rivastigmine. The cytotoxicity of all carbamates was evaluated using standard in vitro test with Jurkat cells. Many of the studied carbamates can be considered as promising compounds for potential medicinal applications with regard to their inhibitory activity as well as negligible cytotoxicity.

TRPV1 Antagonists

Disclosed herein are compounds of formula (I) or pharmaceutically acceptable salts, solvates, or combinations thereof, wherein X1, X2, X3, X4, J, K, L, X5, X6, Rb, G2, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.