52784-31-3

Basic information

• Product Name: 3-PHENYL-CYCLOBUTAN-1-ONE
• Synonyms: 3-PHENYL-CYCLOBUTAN-1-ONE;3-PHENYL-CYCLOBUTANE-1-ONE;AKOS MSC-0146;CHEMBRDG-BB 4002962;3-Phenyl-1-cyclobutanone;3-phenylcyclobutanone(SALTDATA: FREE);1-Oxo-3-phenylcyclobutane
• CAS NO: 52784-31-3
• Molecular Formula: C10H10O
• Molecular Weight: 146.19
• Product Categories: Building Blocks;C10;Carbonyl Compounds;Chemical Synthesis;Ketones;Organic Building Blocks
• Mol File: 52784-31-3.mol
• Article Data: 50

Chemical Properties

• Boiling Point: 258 °C at 760 mmHg
• Flash Point: 105.8 °C
• Appearance: /
• Density: 1.11 g/cm³
• Vapor Pressure: 0.0141mmHg at 25°C
• Refractive Index: 1.544
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-PHENYL-CYCLOBUTAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-PHENYL-CYCLOBUTAN-1-ONE(52784-31-3)
• EPA Substance Registry System: 3-PHENYL-CYCLOBUTAN-1-ONE(52784-31-3)

Safety Data

• Hazard Codes: Xi
• WGK Germany: 3
• Hazardous Substances Data: 52784-31-3(Hazardous Substances Data)

Usage

General Description

3-Phenyl-cyclobutan-1-one is a chemical compound with the chemical formula C10H10O. It is a cyclic ketone with a phenyl group attached to a cyclobutane ring. 3-PHENYL-CYCLOBUTAN-1-ONE has been the subject of research due to its potential pharmaceutical and industrial applications. It is known for its aromatic and potentially bioactive properties, making it a potential candidate for the development of new drugs and materials. Additionally, its unique structure and reactivity make it a valuable intermediate in organic synthesis, with potential uses in the production of fragrances, flavors, and polymers. Overall, 3-phenyl-cyclobutan-1-one is a versatile and potentially valuable chemical compound with a wide range of potential applications.

InChI:InChI=1/C10H10O/c11-10-6-9(7-10)8-4-2-1-3-5-8/h1-5,9H,6-7H2

Upstream product

• 340-01-2 4,4-dichloro-3,3-difluoro-1-phenyl-cyclobutene 
• 150639-15-9 (1s,3s)-3-phenylcyclobutanol 
• 100-42-5 styrene 
• 76-02-8 trifluoroacetyl chloride 
• 14752-66-0 sodium p-chlorobenzenesulphinate 
• 873-55-2 sodium benzenesulfonate 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 100-52-7 benzaldehyde 
• 62912-75-8 methyl 2-methoxy-3-phenyl-2-propenoate 
• 62912-78-1 1-Methoxy-2-phenyl-cyclopropanecarboxylic acid methyl ester 
• 1959-45-1 3,3-difluoro-1-phenylcyclobutene 
• 1813-84-9 1,1-Difluor-3-brom-3-phenyl-cyclobutan 
• 533-65-3 1,1-difluoro-3-phenyl-cyclobutane 
• 536-74-3 phenylacetylene 

Downstream Products

• 2722-36-3 3-phenyl-1-butanol 
• 1008-73-7 4-phenyldihydrofuran-2(3H)-one 
• 1008-73-7 (R)-4-phenyl-4,5-dihydrofuran-2(3H)-one 
• 68844-05-3 4-phenyldihydrofuran-2-one 
• 1533-20-6 1,3-diphenylbutane-1-one 
• 92243-56-6 cis/trans-3-phenylcyclobutanol 
• 1082341-04-5 (3R,4R)-4-{3-[6-(difluoromethoxy)quinolin-4-yl]-3-hydroxypropyl}-1-(3-phenylcyclobutyl)piperidine-3-carboxylic acid 
• 1082341-05-6 (3R,4R)-4-[3-hydroxy-3-(6-methoxy-quinolin-4-yl)propyl]-1-(3-phenyl-cyclobutyl)-piperidine-3-carboxylic acid amide 
• 1082342-80-0 C₃₀H₃₆N₂O₄ 
• 1082338-72-4 C₂₉H₃₄N₂O₄ 
• 1082342-84-4 C₃₀H₃₅FN₂O₃ 
• 1082342-36-6 (S)-1-(6-methoxyquinolin-4-yl)-3-((3R,4R)-1-(3-phenylcyclobutyl)-3-(2H-tetrazol-5-yl)piperidin-4-yl)propan-1-ol 
• 1082342-89-9 (3R,4R)-4-((S)-3-hydroxy-3-(6-methoxyquinolin-4-yl)propyl)-1-(3-phenylcyclobutyl)piperidine-3-carboxamide 
• 1082341-02-3 (3R,4R)-4-[3-hydroxy-3-(6-hydroxyquinolin-4-yl)propyl]-1-(3-phenylcyclobutyl)piperidine-3-carboxylic acid 

Relevant articles and documents

Manganese=Catalyzed Achmatowicz Rearrangement Using Green Oxidant H2O2

Oxidation reactions have been extensively studied in the context of the transformations of biomass=derived furans. However, in contrast to the vast literature on utilizing the stoichiometric oxidants, such as m=CPBA and NBS, catalytic methods for the oxidative furan=recyclizations remain scarcely investigated. Given this, we report a means of manganese=catalyzed oxidations of furan with low loading, achieving the Achmatowicz rearrangement in the presence of hydrogen peroxide as an environmentally benign oxidant under mild conditions with wide functional group compatibility.

Visible-Light-Promoted Selenocyanation of Cyclobutanone Oxime Esters Using Potassium Selenocyanate

We report the visible-light-promoted selenocyanation of cyclobutanone oxime esters using potassium selenocyanate in the presence of a fac-Ir(ppy)3 catalyst for the first time. Because of the mild conditions employed and use of readily accessible potassium selenocyanate, this method is an effective and green strategy for the synthesis of cyano and selenocyano bifunctional substituted alkanes.