909712-10-3Relevant academic research and scientific papers
Radiosynthesis and in vivo evaluation of a fluorine-18 labeled pyrazine based radioligand for PET imaging of the adenosine A2B receptor
Lindemann, Marcel,Hinz, Sonja,Deuther-Conrad, Winnie,Namasivayam, Vigneshwaran,Dukic-Stefanovic, Sladjana,Teodoro, Rodrigo,Toussaint, Magali,Kranz, Mathias,Juhl, Cathleen,Steinbach, J?rg,Brust, Peter,Müller, Christa E.,Wenzel, Barbara
, p. 4650 - 4663 (2018)
On the basis of a pyrazine core structure, three new adenosine A2B receptor ligands (7a–c) were synthesized containing a 2-fluoropyridine moiety suitable for 18F-labeling. Compound 7a was docked into a homology model of the A2B
