91-97-4

Usage

Uses

4,4''-Diisocyanato-3,3''-dimethylbiphenyl is used in preparation method of high-thixotropy single-component modified silane polymer sealant comprising thixotropic agent.

Reactivity Profile

Isocyanates and thioisocyanates, such as 3,3'-Dimethyl-4,4'-biphenylene diisocyanate, are incompatible with many classes of compounds, reacting exothermically to release toxic gases. Reactions with amines, aldehydes, alcohols, alkali metals, ketones, mercaptans, strong oxidizers, hydrides, phenols, and peroxides can cause vigorous releases of heat. Acids and bases initiate polymerization reactions in these materials. Some isocyanates react with water to form amines and liberate carbon dioxide. Base-catalysed reactions of isocyanates with alcohols should be carried out in inert solvents. Such reactions in the absence of solvents often occur with explosive violence, [Wischmeyer(1969)].

Flammability and Explosibility

Notclassified

Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx. See also CYANATES and ESTERS.

Upstream product

• 75-44-5 phosgene 
• 612-82-8 3,3'-dimethylbenzidine diammonium chloride 
• 16083-49-1 N,N'-(3,3'-dimethyl-biphenyl-4,4'-diyl)-bis-carbamic acid dimethyl ester 
• 119-93-7 o-tolidin 
• 124-38-9 carbon dioxide 

Downstream Products

• 34106-66-6 N,N'-(3,3'-dimethyl-biphenyl-4,4'-diyl)-bis-carbamic acid diphenyl ester 
• 117688-75-2 1-Cyclohexyl-3-[4'-(3-cyclohexyl-3-{[(E)-cyclohexylimino]-morpholin-4-yl-methyl}-ureido)-3,3'-dimethyl-biphenyl-4-yl]-1-{[(E)-cyclohexylimino]-morpholin-4-yl-methyl}-urea 
• 349454-57-5 N',N'''-diphenyl-N,N''-(3,3'-dimethyl-biphenyl-4,4'-diyl)-di-urea 
• 3259-65-2 4,4'-bis-(aziridine-1-carbonylamino)-3,3'-dimethyl-biphenyl 

Relevant academic research and scientific papers

Synthesis method for preparing 3,3-dimethyl-4,4-biphenyl diisocyanate by phosgene continuous method

The invention discloses a synthesis method for preparing 3,3-dimethyl-4,4-biphenyl diisocyanate by a phosgene continuous method. A multistage continuous micro-channel reactor is adopted, 3,3-dimethyl-4,4-biphenyl diamine and phosgene are used as raw materials, the micro-channel reactor is adopted for phosgene continuous production, the reaction time is shortened from several h in the prior art toseveral min and generally does not exceed 20 min, and the reaction efficiency is remarkably improved. The selectivity of the product is obviously improved, the byproduct urea is obviously reduced, andthree wastes are reduced. The whole reaction process is a continuous reaction, the process is simple, reaction conditions are accurately controlled, equipment corrosion is small, and safety is high.The reaction yield is increased and reaches 95-98%, the product purity is greater than 99%, and the production cost is low.

Preparation method of dimethyl-biphenyl diisocyanate

The invention relates to a preparation method of dimethyl-biphenyl diisocyanate. The method comprises the steps that firstly, a catalyst polyoxometallate and a solvent are added into a reaction vessel, then raw materials ortho-tolidine, phenylsilane, an acid binding agent and a dehydrating agent are added and uniformly mixed together, finally, gaseous carbon dioxide is added, and magnetic stirringis conducted at a certain temperature for a full reaction to obtain the product. According to the method, M-Anderson-type heteropoly acid is adopted as the catalyst, the catalyst requires mild reaction conditions and is high in specific selectivity, recyclable and environmentally friendly, the cleanliness of the industrial reaction is improved, the economical efficiency of the process is improved, the manufacturing cost and the production of three wastes are reduced, the environmental protection pressure is relieved, and industrial production is facilitated.

Preparation method of 1,5-naphthalene diisocyanate

The invention relates to a preparation method of 1,5-naphthalene diisocyanate. The preparation method comprises the steps that a catalyst polyoxometallate and a solvent are added into a reaction container; then raw materials including 1,5-diaminonaphthalene, phenylsilane, an acid-binding agent and a dehydrating agent are added, and the materials are evenly mixed; finally, gaseous carbon dioxide isadded, the materials are stirred magnetically at a certain temperature for sufficient reaction, and the product is obtained. According to the method, an M-Anderson type heteropoly acid serves as a catalyst, the catalyst is mild in required reaction condition, high in specific selectivity, capable of being recycled and environmentally friendly, the cleanness of industrial reaction is improved, theeconomical efficiency of the technology is improved, the manufacturing cost and generation of three wastes are reduced, the environment-friendly pressure is reduced, and industrial production is facilitated.

Syntheses of isocyanates via amines and carbonyl fluoride

Isocyanates are widely used in many different areas, but the most common synthesis route-phosgene route cannot fit the more and more rigorous restriction of safety and environment. Here, a facile synthesis method of isocyanates via amines and carbonyl fluoride is proven feasibly by expanding its applications to the syntheses of nine different isocyanates. And two differences with the phosgene route are proposed. The reaction could occur under milder conditions and afford isocyanates in good yields, especially for the isocyanates containing electron withdrawing groups. It is appealing for industrial application.

Synthesis of isocyanates from carbamate esters employing boron trichloride

The conversion of carbamate esters to isocyanates and diisocyanates of industrial importance is possible using BCl3 in the presence of Et3N; the reaction is simple in execution and work-up, occurring under mild conditions and affording isocyanates in excellent yields.

Amide waxes

Organic amide waxes having at least two amide groups per molecule are prepared by reacting monocarboxylic acids preferably fatty acids with organic di- or poly-isocyanates; the wax products are useful particularly as lubricants.