910028-95-4

Upstream product

• 910028-91-0 2'-O-pivaloylthiomethyl-uridine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 69304-38-7 3',5'-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 174497-93-9 2'-O-methylthiomethyl-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)uridine 
• 910028-87-4 2'-O-pivaloylthiomethyl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)uridine 

Downstream Products

• 910028-99-8 2'-O-pivaloylthiomethyl-3'-O-(2-trimethylsilylethyl N,N-diisopropylphosphoramidite)-5'-O-(4,4'-dimethoxytrityl)uridine 

Relevant academic research and scientific papers

First evaluation of acyloxymethyl or acylthiomethyl groups as biolabile 2′-O-protections of RNA

Short oligo-U sequences containing 2′-O-acyloxymethyl or acylthiomethyl groups as biolabile 2′-O-protections of RNA have been synthesized. These modified homouridylates are deprotected upon cellular esterase activation to release the parent RNA. They exhi