910099-87-5

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 183201-49-2 (R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol 
• 185030-09-5 (R)-α-(cyclopentyl-1-ene)-α-hydroxyl-α-phenylacetic acid 
• 116907-30-3 (2R,5R)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one 
• 909298-90-4 (2R,5S)-2-(tert-butyl)-5-phenyl-5-(1-hydroxycyclopentyl)-1,3-dioxolan-4-one 
• 910099-85-3 (2R,5S)-2-(tert-butyl)-5-phenyl-5-(cyclopent-1-enyl)-1,3-dioxolan-4-one 
• 64471-45-0 (2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid 

Downstream Products

• 114121-68-5 (R)-(-)-3-[(R)-2-hydroxy-2-cyclopentyl-2-phenylethoxy]-1-azabicyclo[2.2.2]octane 
• 114121-68-5 (R)-2-[(S)-(1-Aza-bicyclo[2.2.2]oct-3-yl)oxy]-1-cyclopentyl-1-phenyl-ethanol 
• 852461-44-0 (R)-1-phenyl-1-cyclopentylethylene oxide 

Relevant academic research and scientific papers

A quaternary ammonium salt of pentethyl quinamidine optical isomer, pharmaceutical composition and its medical use

The invention relates to a quaternary ammonium salt compound shown as a formula I, or pharmaceutically acceptable salt or solvate thereof. The invention also relates to application of the compound as a selective M receptor antagonist, particularly a selec

Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018)

A practical diastereoselective synthetic method for 8018 enantiopure isomers is described. The intramolecular asymmetric epoxidation of mono-sulfonate 4 was applied for the execution of the synthesis of the key chiral building block for the first time. The isomers were obtained with 70-76% yields in 99-100% ee.