183201-49-2

Usage

Uses

Used in Pharmaceutical Industry:
(R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol is used as a chiral building block for the synthesis of chiral drugs. Its application is based on the compound's ability to serve as a key component in the creation of pharmaceuticals that require specific stereochemistry for their intended effects.
Used in Agrochemicals:
In the agrochemical industry, (R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol is used as a chiral building block for the development of chiral pesticides and other agrochemicals. (R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol's chirality allows for the production of targeted and efficient products that can minimize environmental impact.
Used in Flavor Industry:
(R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol is utilized as a chiral building block in the flavor industry to create flavors with specific stereochemical properties. (R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol's chirality is crucial in developing flavors that can provide unique taste profiles and enhance the sensory experience.
Used in Chemical Research and Development:
(R)-α-phenyl-α-cyclopentyl-α-hydroxyethanol is employed as a valuable compound in chemical research and development. Its application lies in its potential to contribute to the advancement of asymmetric synthesis and chiral catalysis, furthering the understanding and capabilities within these scientific fields.

Upstream product

• 64471-45-0 (2R)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid 
• 185030-09-5 (R)-α-(cyclopentyl-1-ene)-α-hydroxyl-α-phenylacetic acid 
• 116907-30-3 (2R,5R)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one 
• 909298-90-4 (2R,5S)-2-(tert-butyl)-5-phenyl-5-(1-hydroxycyclopentyl)-1,3-dioxolan-4-one 
• 910099-85-3 (2R,5S)-2-(tert-butyl)-5-phenyl-5-(cyclopent-1-enyl)-1,3-dioxolan-4-one 
• 427-49-6 2-cyclopentyl-2-hydroxy-2-phenylacetic acid 
• 75366-33-5 1-cyclopentyl-1-phenylethene 

Downstream Products

• 852461-44-0 (R)-1-phenyl-1-cyclopentylethylene oxide 
• 114121-68-5 (R)-(-)-3-[(R)-2-hydroxy-2-cyclopentyl-2-phenylethoxy]-1-azabicyclo[2.2.2]octane 
• 114121-68-5 (R)-2-[(S)-(1-Aza-bicyclo[2.2.2]oct-3-yl)oxy]-1-cyclopentyl-1-phenyl-ethanol 
• 910099-87-5 (R)-α-phenyl-α-cyclopentyl-α-hydroxyethyl p-toluenesulfonate 

Relevant academic research and scientific papers

Synthesis of the optical isomers of a new anticholinergic drug, penehyclidine hydrochloride (8018)

A practical diastereoselective synthetic method for 8018 enantiopure isomers is described. The intramolecular asymmetric epoxidation of mono-sulfonate 4 was applied for the execution of the synthesis of the key chiral building block for the first time. The isomers were obtained with 70-76% yields in 99-100% ee.

CLASS OF BIFUNCTIONAL COMPOUNDS WITH QUATERNARY AMMONIUM SALT STRUCTURE

The invention provides a class of compounds represented by formula (I), having bifunctional active quaternary ammonium salt structure of a β2-adrenoreceptor agonist and an M receptor antagonist, a pharmaceutically acceptable salt, solvate, and optical isomer thereof. A pharmaceutical composition comprising such a compound with quaternary ammonium salt structure, a method for preparing such a compound with quaternary ammonium salt structure and an intermediate thereof, and uses thereof in treating pulmonary disorders are also provided. The compounds of the invention have high selectivity to the M receptor subtype, and have less adverse reaction and lower toxic and side effects in the treatment of pulmonary diseases such as COPD and asthma.

A quaternary ammonium salt of pentethyl quinamidine optical isomer, pharmaceutical composition and its medical use

The invention relates to a quaternary ammonium salt compound shown as a formula I, or pharmaceutically acceptable salt or solvate thereof. The invention also relates to application of the compound as a selective M receptor antagonist, particularly a selec