910136-49-1Relevant articles and documents
Total synthesis of antofine using the net [5+5]-cycloaddition of γ,δ-unsaturated carbene complexes and 2-alkynylphenyl ketones as a key step
Camacho-Davila, Alejandro,Herndon, James W.
, p. 6682 - 6685 (2007/10/03)
A compound containing all of the carbons of the anticancer agent antofine was produced in a single step from the coupling of a γ,δ-unsaturated carbene complex with a 2-alkynylphenyl ketone derivative. Subsequent conversion to antofine was effected in three steps.